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Fig. 5 | Gut Pathogens

Fig. 5

From: Two putative MmpL homologs contribute to antimicrobial resistance and nephropathy of enterohemorrhagic E. coli O157:H7

Fig. 5

Histopathological analysis of H and E stained kidneys slides: Control and WT groups. a Control group: Both photos show the normal histological structure of renal parenchyma without any pathological features. b WT group: Vacuolation of renal tubular epithelium (short arrow), perivascular inflammatory cells infiltration (long arrow) and congestion of renal blood vessels (arrow head) (left), proteinaceous material in the lumen of renal tubules (arrow) (right). c ΔyegN group: Congestion of renal blood vessels (short arrow) and glomerular tuft (long arrow) (left), slight vacuolation of some renal tubular epithelium (short arrow) and congestion of renal blood vessels (long arrow) (right). d Δz4861 group: congestion of renal blood vessels (long arrow) (left), both photos show slight vacuolation of some renal tubular epithelium represented by the short arrow (left), or the arrow (right). e ΔzΔy group: Congestion of renal blood vessels (small arrow) and glomerular tuft (large arrow) (left), while the right photo does not show any histopathological changes. Note that the entire experiment was repeated twice on two different sets of mice, and the presented results are collective of both trials

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