Two putative MmpL homologs contribute to antimicrobial resistance and nephropathy of enterohemorrhagic E. coli O157:H7

Table 1 Evaluation of histopathological lesions caused by wild-type and mutant strains

Histopathological lesion	C	WT	Δz4861	ΔyegN	Δz Δy
Congestion of renal blood vessels	−	+++	+	++	+
Congestion of glomerular tuft	−	+++	+	+	+
Vacuolation of renal tubular epithelium	−	+++	+	+	±
Proteinaceous material in the lumen of renal tubules	−	++	−	−	−
Focal interstitial inflammatory cells infiltration	−	++	−	+	−

C control, WT wild-type strain; (−) no change, (+) mild change, (++) moderate change, (+++) severe change

ISSN: 1757-4749