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Table 1 Evaluation of histopathological lesions caused by wild-type and mutant strains

From: Two putative MmpL homologs contribute to antimicrobial resistance and nephropathy of enterohemorrhagic E. coli O157:H7

Histopathological lesion C WT Δz4861 ΔyegN Δz Δy
Congestion of renal blood vessels +++ + ++ +
Congestion of glomerular tuft +++ + + +
Vacuolation of renal tubular epithelium +++ + + ±
Proteinaceous material in the lumen of renal tubules ++
Focal interstitial inflammatory cells infiltration ++ +
  1. C control, WT wild-type strain; (−) no change, (+) mild change, (++) moderate change, (+++) severe change