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Fig. 2 | Gut Pathogens

Fig. 2

From: Cytokines derived from innate lymphoid cells assist Helicobacter hepaticus to aggravate hepatocellular tumorigenesis in viral transgenic mice

Fig. 2

Helicobacter hepaticus potentiated hepatocellular tumorigenesis in HBV-transgenic mice. a Experimental protocol. H. hepaticus (2 × 107 CFU) was gavaged into 4–5-month-old HBs-Tg and B6 mice every 48 h for 8 months. b Tumorigenesis incidence in each group (n = 6). c Liver tumor nodule numbers in each group (n = 6). d Serum AFP activity for each group (n = 6). e Representative H&E sections of livers in each group at 13 months old. f Survival of each group (n = 6). Data are expressed as median ± percentile. Mann–Whitney U and Log-rank (Mantel-Cox) test was used respectively. P < 0.05 represents statistical difference. *P < 0.05, **P < 0.01

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