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Fig. 4 | Gut Pathogens

Fig. 4

From: Cytokines derived from innate lymphoid cells assist Helicobacter hepaticus to aggravate hepatocellular tumorigenesis in viral transgenic mice

Fig. 4

ILC-derived IFN-γ triggered epithelial–mesenchymal transition via STAT1 signaling in Helicobacter hepaticus-associated HCC. a Hepatic E-cadherin relative expression at different ages in wild type B6 and HBs-Tg. b Hepatic E-cadherin relative expression in H. hepaticus adopted HBs-Tg mice with IFN-γ antibody. c Hepatic signaling pathways detected by western blotting at 13 months old. d Detection of E-cadherin and EMT-related genes in primary hepatocytes with IFN-γ and inhibitor. Data are expressed as median ± percentile. Mann–Whitney U was used. P < 0.05 represents statistical difference. *P < 0.05, **P < 0.01

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Gut Pathogens

ISSN: 1757-4749