Table 5 GyrA mutations in sequenced levofloxacin-resistant H. pylori strains
Strain | MIC (µg/ml) | Mutation(s) |
|---|---|---|
KH1 | 4 | D91N, N87K |
KH2 | 4 | R295H |
KH3 | 4 | D91N |
KH6 | 4 | D91G |
KH8 | 4 | D91N |
KH9 | 4 | D91N |
KH12 | 2 | D91N |
KH13 | 4 | D91N |
KH14 | 4 | N87I |
KH15 | 4 | D91G |
KH16 | 4 | – |
KH17 | 4 | D91G |
KH18 | 4 | N87K |
KH19 | 4 | D91N |
KH20 | 4 | 5-amino-acid N-terminal extension |
KH21 | 4 | D91N |
KH25 | 4 | D91Y |
KH26 | 4 | N87K |
KH27 | 4 | D91Y |
KH28 | 4 | D91Y |
KH30 | 4 | D91N |
KH32 | 4 | D91G |
KH33 | 4 | D91N |
KH36 | 4 | N87K |
KH37 | 4 | D91N |
KH38 | 4 | N87K |
KH40 | 4 | 5-amino-acid N-terminal extension |
KH41 | 4 | N87K |
KH43 | 4 | D91N |
KH44 | 4 | N87K |
KH45 | 4 | N87K |