From: Proton pump inhibitors and 180-day mortality in the elderly after Clostridium difficile treatment
Type | Survivors (765) | Died (109) | p value |
---|---|---|---|
n % | n % | ||
Severe infection | 126 (16.5) | 29 (26.6) | 0.010 |
Hospital acquired | 365 (47.7) | 87 (79.8) | < 0.001 |
Antibiotic regimens | |||
IV Flagyl | 147 (19.2) | 33 (30.3) | 0.008 |
Oral Flagyl | 355 (46.4) | 31 (28.4) | < 0.001 |
Oral Vanco | 360 (47.1) | 63 (57.8) | 0.036 |
Combo | 87 (11.4) | 13 (11.9) | 0.87 |
Bacterial other | 335 (43.8) | 72 (66.1) | < 0.001 |
Other medications | |||
PPI | 296 (38.7) | 24 (22.0) | 0.001 |
H2 blocker | 46 (6.0) | 4 (3.7) | 0.41 |
Corticosteroids | 75 (9.8) | 7 (6.4) | 0.26 |
Probiotic | 54 (7.1) | 1 (0.9) | 0.014 |