Inheritance model | 1 | 2 | 3 | 4 | 5 | 6 |
---|---|---|---|---|---|---|
Sequence ontology | 24,623 | 26,950 | 24,623 | 26,950 | 29,197 | 29,612 |
European allele frequency ≤ 0.05 or missing | 11,024 | 12,864 | 3144 | 13,899 | 15,089 | 15,592 |
Variants shared among affected members | 903 | 655 | 974 | 1432 | 1869 | 1500 |
Variants absent from normal or not called | 110 | 96 | 2 | 16 | 73 | 2 |
Sequence read depth ≥ 10 for all patients | 95 | 89 | 1 | 15 | 68 | 1 |
Polyphen = possibly or probably damaging or | 57 | 56 | 1 | 14 | 41 | 1 |
Inheritance model | 7 | 8 | 9 | 10 | 11 | 12 |
---|---|---|---|---|---|---|
Sequence ontology | 24,623 | 26,950 | 24,623 | 26,949 | 29,197 | 29,612 |
European Allele ≤ frequency 0.05 or missing | 11,024 | 12,864 | 3144 | 13,898 | 15,089 | 15,592 |
Variants shared among affected members | 2228 | 1213 | 1012 | 1636 | 3239 | 1816 |
Variants absent from normal or not called | 577 | 292 | 6 | 34 | 353 | 14 |
Sequence read depth ≥ 10 for all patients | 142 | 111 | 2 | 17 | 73 | 3 |
Polyphen = possibly or probably damaging or | 91 | 74 | 1 | 16 | 45 | 2 |