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Table 4 The Vibrant GPP array's performance evaluation with validated positive specimens

From: Evaluation of the Vibrant DNA microarray for the high-throughput multiplex detection of enteric pathogens in clinical samples

Organism Comparator (culture or RT-PCR) Vibrant GPP array Agreement (95% CI)
Culture isolates Clinical samples Culture isolates Clinical samples
Bacteria
 E. coli O157:H7 2 7 2 7 100 (66.4–100)
 Enteroaggregative E. coli (EAEC) 2 3 2 3 100 (47.8–100)
 Enteropathogenic E. coli (EPEC) 1 4 1 4 100 (47.8–100)
 Enterotoxigenic E. coli (ETEC) lt/st 2 6 2 6 100 (63.1–100)
 Shiga-like toxin producing E. coli (STEC) stx1/stx2 2 9 2 9 100 (71.5–100)
 Plesiomonas shigelloides 1 8 1 8 100 (66.4–100)
 Vibrio parahaemolyticus 1 7 1 7 100 (63.1–100)
 Vibrio vulnificus 1 6 1 6 100 (59.0–100)
 Helicobacter pylori 2 3 2 3 100 (47.8–100)
 Listeria spp. 1 6 1 6 100 (59.0–100)
 Vibrio cholerae 1 3 1 3 100 (39.8–100)
 C. difficile toxin A/B 1 9 1 9 100 (69.2–100)
 Salmonella spp. 3 8 3 8 100 (71.5–100)
 Shigella/Enteroinvasive E. coli (EIEC) 3 5 3 5 100 (63.1–100)
 Yersinia enterocolitica 1 5 1 5 100 (54.1–100)
 Campylobacter jejuni 2 3 2 3 100 (47.8–100)
 Campylobacter upsaliensis 1 3 1 3 100 (39.8–100)
Parasite
 Giardia lamblia 1 3 1 3 100% (39.8–100)
 Cryptosporodium spp. 2 8 2 8 100% (69.2–100)
 Entamoeba histolytica 7 2 7 2 100% (66.4–100)
 Cyclospora cayetanensis 2 4 2 4 100% (54.1–100)
Virus
 Norovirus GI 2 9 2 9 100% (71.5–100)
 Norovirus GII 2 3 2 3 100% (47.8–100)
 Rotavirus A 1 7 1 7 100% (63.1–100)
 Adenovirus F 40/41 1 10 1 10 100% (71.5–100)
 Astrovirus 1 9 1 9 100% (69.2–100)
 Sapovirus (I, II, IV, V) 1 2 1 2 100% (29.2–100)
Fungi
 Candida spp. 1 6 1 6 100% (59.0–100)
 Microsporidium spp. 1 1 1 1 100% (15.8–100)
  1. **P < 0.00001 (Chi square test) for culture versus the Vibrant GPP array