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Table 2 Frequently modulated miRNA expression in HBV related liver diseases

From: Exosomal miRNAs in hepatitis B virus related liver disease: a new hope for biomarker

Clinical stagemiRNAGenomic LocationExpressionRefs.
Chronic HBVmiR-12218q21.3Up regulation[67, 68]
miR- 2049q21.12Down regulation[69]
Let7c21q21.1Up regulation[68]
miR-23b9q22.32Up regulation[68]
miR-15019 q13.33Up regulation[68]
Liver cirrhosis/FibrosismiR-297q32.3Down regulation[70,71,72,73]
miR-133a18q11.2Down regulation[74]
miR-1999q34.11up regulation[75]
miR-214 5p1q24.3Up regulation[76]
miR-221/222Xp11.3Up regulation[77]
Hepatocellular carcinoma(*) miR-17-92 cluster13q31.3Up regulation[78]
miR-2117q23.2Up regulation[78]
miR-967q32.2Up regulation[79]
miR-3752q35Up regulation[80]
miR-92a5q14.3Up regulation[80]
miR-101-11p31.3Down regulation[81]
miR-199b9q34.11Down regulation[81]
miR-244Xq28Up regulateion[81]
miR-15521q21.3Up regulateion[82]
miR-12218q21.3Down regulation[83]
miR-1455q32Down regulation[84]
miR-13217p13.3Down regulation[85]
miR-34a1p36.22Down regulation[58]
miR-23a19p13.12Down regulation[86]
miR-148a7p15.2Down regulation[87]
miR-19211q13.1Down regulation[88]
miR-125b11q24.1Down regulation[89]
miR-2001p36.33Down regulation[90]
miR-6029q34.3Up regulation[91]
  1. (*) miR-17-92 cluster (miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92a-1)