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Table 2 Nucleotide changes in H. pylori 26695 TF generated by transformation of 26695 with 26695 EZA genomic DNA

From: Antibacterial activity of ethoxzolamide against Helicobacter pylori strains SS1 and 26695

Positiona

Type

Reference

Allele

Locus tag

Amino acid substitution

Gene product

1367889

Substitution

C

T

HP_1293

Glu290Lys

RNA polymerase subunit α

1197822

Substitution

C

T

HP_1134

ATP synthase subunit α

1198143

Deletion

TC

Ribosome-binding site for HP_1134

1198189

Substitution

T

C

HP_1135

Glu171Lys

ATP synthase subunit δ

1296698

Substitution

T

C

HP_1221

Asn131Asp

UPP pyrophosphate synthase

1548534

Substitution

A

C

HP_1476

Gly60Ala

Flavin prenyltransferase UbiX

835376

Substitution

T

C

HP_0781

Ala92Val

Hypothetical protein

835407

Substitution

A

C

Asp102Glu

835710

Substitution

G

A

Thr201Ala

  1. aNucleotide positions are indicated with reference to the published H. pylori 26695 genome (GenBank ID: AE000511 [18])