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Table 2 Performance of multiplex ARMS-PCR for detection of H. pylori infection and antibiotic resistance in 192 gastric biopsy samples

From: Evaluation of multiplex ARMS-PCR for detection of Helicobacter pylori mutations conferring resistance to clarithromycin and levofloxacin

Parameters

H. pylori

Clarithromycin resistance

Levofloxacin resistance

Clarithromycin and Levofloxacin resistance

Sequencing

Sequencing

Sequencing

Sequencing

 

+

-

 

+

-

 

+

-

 

+

-

 

 +

108

4

112

53

0

53

50

7

57

30

5

35

 _

0

80

80

0

139

139

1

134

135

0

157

157

 

108

84

192

53

139

192

51

141

192

30

162

192

Sensitivity

100%

100%

98.04%

100%

Specificity

95.24%

100%

95.04%

96.91%

PPV

97.92%

100%

95.83%

97.40%

Kappa

0.96

1.00

0.90

0.91