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Table 2 Performance of multiplex ARMS-PCR for detection of H. pylori infection and antibiotic resistance in 192 gastric biopsy samples

From: Evaluation of multiplex ARMS-PCR for detection of Helicobacter pylori mutations conferring resistance to clarithromycin and levofloxacin

Parameters H. pylori Clarithromycin resistance Levofloxacin resistance Clarithromycin and Levofloxacin resistance
Sequencing Sequencing Sequencing Sequencing
  + -   + -   + -   + -  
 + 108 4 112 53 0 53 50 7 57 30 5 35
 _ 0 80 80 0 139 139 1 134 135 0 157 157
  108 84 192 53 139 192 51 141 192 30 162 192
Sensitivity 100% 100% 98.04% 100%
Specificity 95.24% 100% 95.04% 96.91%
PPV 97.92% 100% 95.83% 97.40%
Kappa 0.96 1.00 0.90 0.91