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Table 2 Antibiotic susceptibilities of mcr-1-like positive donor strains and transconjugants (MICs in mg/L)

From: Genome sequences of two clinical Escherichia coli isolates harboring the novel colistin-resistance gene variants mcr-1.26 and mcr-1.27

Strain no. AMP CTX CAZ FOXb GEN AMK STRb CMP TETb NALb CIP MER TRS COL
803/18 E. coli (B1, ST155)a > 16 ≤ 1 ≤ 2 4 1 ≤ 2 > 64 8 > 8 > 32 0.5 ≤ 0.063 > 128 4
803/18 Tc1 E. coli J53 Azir (A, ST10)a > 16 ≤ 1 ≤ 2 8 4 16 > 64 ≤ 4 1 16 ≤ 0.063 ≤ 0.063 ≤ 4 2
844/18 E. coli (D, ST69)a > 16 ≤ 1 ≤ 2 8 2 4 16 > 32 >8 > 32 0.5 ≤ 0.063 > 128 4
844/18 Tc1 E. coli J53 Azir (A, ST10)a 4 ≤ 1 ≤ 2 4 ≤ 0.5 ≤ 2 ≤ 4 32 >8 8 ≤ 0.063 0.125 > 128 2
E. coli J53 Azir (A, ST10)a recipient 4 ≤ 1 ≤ 2 2 ≤ 0.5 ≤ 2 ≤ 4 8 1 8 ≤ 0.063 ≤ 0.063 ≤ 4 0.125
  1. Antibiotic susceptibility testing was performed by broth microdilution with MIC interpretation of minimum inhibitory concentrations (MICs) according recommendations of the European Committee on Antimicrobial Susceptibility testing (EUCAST v 10.0). Tc1, transconjugants; aE. coli phylogentic group determined by PCR according Clermont et al. [8], and multilocus sequence type (ST) according to the MLST scheme of Achtmann (Wirth et al. [12]). bFor these substance only epidemiological cut-off values (ECOFFs) are available to separates microorganisms without (wild type) and with acquired resistance mechanisms (non-wild type) to the agent in question (http://www.eucast.org)
  2. AMP ampicillin, CTX cefotaxime, CAZ ceftazidime, FOX cefoxitin, GEN gentamicin, AMK amikacin, STR streptomycin, NAL nalidixic acid, CMP chloramphenicol, TET tetracycline, CIP ciprofloxacin, MER meropenem, TRS trimethoprim/sulfamethoxazole, COL colistin