Table 1 Comparison of the general status of the patients from the three groups before the intervention
From: The prophylactic effects of BIFICO on the antibiotic-induced gut dysbiosis and gut microbiota
| Parameter |
Control group (n = 64) | Regular group (n = 67) | Double-dosage group (n = 65) | P-value |
|---|---|---|---|---|
| Age (years) (x ± s) | 62.83 ± 16.97 | 66.99 ± 12.93 | 66.89 ± 13.92 | 0.187 |
| Gender (Male) (n, %) | 37 (57.81%) | 35 (52.24%) | 44 (67.69%) | 0.189 |
|
Infection site (n) Respiratory system Non-respiratory system Inflammatory marker (x ± s) |
28 36 |
31 36 |
24 41 | 0.533 |
| WBC (109 /L) | 8.15 ± 3.29 | 8.40 ± 3.85 | 8.18 ± 3.69 | 0.911 |
| CRP (mg/L) | 54.72 ± 43.20 | 60.95 ± 41.32 | 59.09 ± 40.31 | 0.681 |
| PCT (ng/mL) | 0.20 ± 0.16 | 0.24 ± 0.17 | 0.23 ± 0.20 | 0.397 |
| Length of hospitalization (days) M (P25, P75) | 17.5 (12, 29.75) | 19 (14, 33) | 25 (15, 36) | 0.081 |
| Duration of antibiotic usage (days) (x ± s) | 12.22 ± 4.84 | 11.21 ± 4.37 | 11.60 ± 4.09 | 0.426 |
|
Type of antibiotic (n) Carbapenem Non-carbapenem |
50 14 |
47 20 |
49 16 | 0.566 |