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Table 1 Comparison of the general status of the patients from the three groups before the intervention

From: The prophylactic effects of BIFICO on the antibiotic-induced gut dysbiosis and gut microbiota

Parameter Control group
(n = 64)
Regular group (n = 67) Double-dosage group (n = 65) P-value
Age (years) (x ± s) 62.83 ± 16.97 66.99 ± 12.93 66.89 ± 13.92 0.187
Gender (Male) (n, %) 37 (57.81%) 35 (52.24%) 44 (67.69%) 0.189
Infection site (n)
Respiratory system
Non-respiratory system
Inflammatory marker (x ± s)
28
36
31
36
24
41
0.533
WBC (109 /L) 8.15 ± 3.29 8.40 ± 3.85 8.18 ± 3.69 0.911
CRP (mg/L) 54.72 ± 43.20 60.95 ± 41.32 59.09 ± 40.31 0.681
PCT (ng/mL) 0.20 ± 0.16 0.24 ± 0.17 0.23 ± 0.20 0.397
Length of hospitalization (days) M (P25, P75) 17.5 (12, 29.75) 19 (14, 33) 25 (15, 36) 0.081
Duration of antibiotic usage (days) (x ± s) 12.22 ± 4.84 11.21 ± 4.37 11.60 ± 4.09 0.426
Type of antibiotic (n)
Carbapenem
Non-carbapenem
50
14
47
20
49
16
0.566
  1. WBC white blood cell count, CRP C-reactive protein, PCT procalcitonin