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Table 1 Comparison of the general status of the patients from the three groups before the intervention

From: The prophylactic effects of BIFICO on the antibiotic-induced gut dysbiosis and gut microbiota

Parameter

Control group

(n = 64)

Regular group (n = 67)

Double-dosage group (n = 65)

P-value

Age (years) (x ± s)

62.83 ± 16.97

66.99 ± 12.93

66.89 ± 13.92

0.187

Gender (Male) (n, %)

37 (57.81%)

35 (52.24%)

44 (67.69%)

0.189

Infection site (n)

Respiratory system

Non-respiratory system

Inflammatory marker (x ± s)

28

36

31

36

24

41

0.533

WBC (109 /L)

8.15 ± 3.29

8.40 ± 3.85

8.18 ± 3.69

0.911

CRP (mg/L)

54.72 ± 43.20

60.95 ± 41.32

59.09 ± 40.31

0.681

PCT (ng/mL)

0.20 ± 0.16

0.24 ± 0.17

0.23 ± 0.20

0.397

Length of hospitalization (days) M (P25, P75)

17.5 (12, 29.75)

19 (14, 33)

25 (15, 36)

0.081

Duration of antibiotic usage (days) (x ± s)

12.22 ± 4.84

11.21 ± 4.37

11.60 ± 4.09

0.426

Type of antibiotic (n)

Carbapenem

Non-carbapenem

50

14

47

20

49

16

0.566

  1. WBC white blood cell count, CRP C-reactive protein, PCT procalcitonin