Fig. 3From: Mechanisms and microbial influences on CTLA-4 and PD-1-based immunotherapy in the treatment of cancer: a narrative reviewEffects of Bifidobacterium +/- PD-1 therapy on tumor size in mice. Oral administration of Bifidobacterium (BIF) improved tumor progression to the same degree as the PD-1 blockade in tumor-bearing mice. Mice treated with BIF + anti-PD-1 therapy resulted in almost complete arrest of tumor growth in this figure [22]. Figure taken from Sivan et al.Back to article page