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Fig. 4 | Gut Pathogens

Fig. 4

From: Mechanisms and microbial influences on CTLA-4 and PD-1-based immunotherapy in the treatment of cancer: a narrative review

Fig. 4

Effects of the abundance of Faecalibacterium and diversity of gut bacteria on progression-free survival in melanoma patients on PD-1 therapy. Melanoma patients on PD-1 therapy who had an increased concentration of Faecalibacterium (F. prausnitzii) in their gut microbiome experienced longer progression-free survival compared to those with low abundance. Patients with increased diversity of bacterial species in their gut microbiome also experienced longer progression-free survival [37]. Figures taken from Gopalakrishnan et al.

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