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Fig. 1 | Gut Pathogens

Fig. 1

From: Fusobacterium nucleatum infection correlates with two types of microsatellite alterations in colorectal cancer and triggers DNA damage

Fig. 1

Fn DNA load in MSS, L/E and MSI-H CRCs. (a) Discovery cohort from North Carolina, USA. (b) Validation cohort from Mie, Japan. Absolute Fn DNA weight was normalized by the absolute tumor DNA weight present in the same DNA sample. Normalized values were converted to logarithmic scales. The data is depicted in the boxplot. Brown, blue and orange boxes represent the distribution of Fn DNA in MSS, L/E and MSI-H CRC, respectively. The thick horizontal line within in each box represents the median Fn DNA load. Dots in MSS column in the USA cohort represents outliers. The statistical difference in Fn DNA loads among MSS, L/E and MSI-H was tested using the Wilcoxon rank sum test. A p-value that is less than 0.05 is considered significant

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