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Fig. 3 | Gut Pathogens

Fig. 3

From: MiR-146a rs2910164 G > C polymorphism modulates Notch-1/IL-6 signaling during infection: a possible risk factor for Crohn’s disease

Fig. 3

Upregulation of Notch-1 and IL-6 in the blood of CD patients and the effect of Mycobacterium avium paratuberculosis (MAP) infection on Notch-1 and IL-6 levels. a, b Expression levels of Notch-1 and IL-6 were measured in peripheral leukocytes isolated from CD and healthy controls (n = 4). c Circulating IL-6 levels were measured in the plasma of CD and healthy controls (n = 22). d, e Expression levels of Notch-1 and IL-6 were measured in peripheral leukocytes isolated from MAP positive and MAP negative individuals (n = 4). f Circulating IL-6 levels were measured in the plasma of MAP positive and MAP negative individuals (n = 22). Gene expression levels were measured using RT-PCR. Plasma IL-6 levels were measured using ELISA. Data are shown as mean ± SD, and significant is considered as *P < 0.05

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Gut Pathogens

ISSN: 1757-4749