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Fig. 2 | Gut Pathogens

Fig. 2

From: Adherent invasive Escherichia coli (AIEC) strain LF82, but not Candida albicans, plays a profibrogenic role in the intestine

Fig. 2

Chronic AIEC LF82 and C. albicans administration induced intestinal inflammation in DSS-induced chronic colitis in mice. Colonic gene expression of: a proinflammatory cytokines Il1b, Il6, Il12b, Il17, Ifng and chemokine Ccl4; b immune cell recruitment markers Adgre1, Ly6g and Cd3e, and T-cell transcription factors Tbx21, Gata3, Rorc and Foxp3. Results correspond to fold-increase when compared to mice receiving drinking water and are expressed as means ± SEM; *P < 0.05; **P < 0.01; ***P < 0.001 for colonized vs. non-colonized mice receiving DSS only (Mann–Whitney U test)

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