Table 1 Demographics, clinical and oral conditions of subjects (n = 50)
From: Ectopic gut colonization: a metagenomic study of the oral and gut microbiome in Crohn’s disease
Crohn's disease (CD) | Healthy controls (HC) | |
|---|---|---|
Mean age* (Range) | 40 (23–67) | 40 (21–66) |
Race | ||
Han Chinese | 13 | 13 |
Malay | 3 | 3 |
Indian | 9 | 9 |
Sex | ||
Male | 10 | 10 |
Female | 15 | 15 |
Oral condition | ||
Mean DMFT^ | 6.5 ± 7.0 | 4.6 ± 5.0 |
Periodontitis present | 5 | 5 |
Smoking | ||
Non-smoker | 20 | 21 |
Previous/current smoker | 5 | 4 |
CD condition | ||
Length of diagnosis in years (range) | 7.8 (1–20) | |
Crohn’s Disease Activity Index (CDAI) | 86.2 ± 87.1 | |
Current disease activity: Active (Diarrhoea, Abdominal pain, Blood-in-stool, fever and fatigue) | 10 | |
Drug regimen# | ||
Steroids/Anti-inflammatory (Mesalazine) | 8 | |
Azathioprine | 13 | |
Biologics | 11 | |
Others (Tacrolimus, sulphasalazine) | 2 | |