Table 3 Clinical characteristics of subjects with concordant gut and oral S. salivarius strains
From: Ectopic gut colonization: a metagenomic study of the oral and gut microbiome in Crohn’s disease
| CD subjects with concordant strains (n = 4) | CD subjects with no concordant strain (n = 21) | p-value | |
|---|---|---|---|
| Crohn’s Disease Activity Index (CDAI)# | 184.3 ± 2.9 | 67.1 ± 82.5 | *0.012 |
| Disease status | |||
| Active disease at time of sampling (Diarrhoea/abdominal pain/blood-in-stool/fever and fatigue) | 4 | 6 | *0.016 |
| Inactive disease at time of sampling | 0 | 15 | |
| Proton Pump Inhibitor use | 1.000 | ||
| Yes | 1 | 7 | |
| No | 3 | 14 | |
| Mean age# | 38 ± 14 | 40 ± 14 | 0.774 |
| Race | 0.056 | ||
| Han Chinese | 4 | 9 | |
| Malay | 0 | 3 | |
| Indian | 0 | 9 | |
| Sex | 0.142 | ||
| Male | 3 | 7 | |
| Female | 1 | 14 | |
| Oral condition | 0.661 | ||
| DMFT# | 5.0 ± 4.2 | 6.8 ± 7.4 | |
| Periodontitis | 0.451 | ||
| Present | 1 | 4 | |
| Absent | 3 | 17 | |