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Table 1 Distribution of virulence genotypes among 269 H. pylori-positive patients with different geographic regions

From: Geographic distribution of the cagA, vacA, iceA, oipA and dupA genes of Helicobacter pylori strains isolated in China

Genetypes

No. of isolates

SD (n = 74)

GX (n = 78)

HN (n = 46)

QH (n = 33)

HL (n = 38)

Total (n = 269)

cagA

70(94.6)

74(94.9)

46(100)

33(100)

38(100)

261(97)

vacA

      

 s1

72(97.3)

78(100)

45(97.8)

30(90.9)

38(100)

263(97.8)

 s2

2(2.7)

0

1(2.2)

3(9.1)

0

6(2.2)

 m1

30(40.5)

14(17.9)

10(21.7)

6(18.2)

12(31.6)

72(26.8)

 m2

43(58.1)

61(78.2)

35(76.1)

26(78.8)

25(65.8)

190(70.6)

 i1

66(89.2)

71(91)

46(100)

29(87.9)

38(100)

250(92.9)

 i2

8(10.8)

7(9)

0

4(12.1)

0

19(7.1)

 s1i1m1

22(29.7)

12(15.4)

10(21.7)

6(18.2)

12(31.6)

62(23)

 s1i1m2

42(56.8)

53(67.9)

34(73.9)

22(66.7)

25(65.8)

176(65.4)

 s1i2m1

7(9.6)

2(2.6)

0

0

0

9(3.3)

 s1i2m2

0

5(6.4)

0

1(3)

0

6(2.2)

 s2i1m1

0

0

0

0

0

0

 s2i1m2

1(1.4)

0

1(2.2)

0

0

2(0.7)

 s2i2m1

1(1.4)

0

0

0

0

1(0.4)

 s2i2m2

0

0

0

3(9.1)

0

3(1.1)

iceA1

49(66.2)

50(64.1)

38(82.6)

24(72.7)

26(68.4)

187(69.5)

iceA2

12(16.2)

20(25.6)

8(17.4)

6(18.2)

8(21.1)

54(20.1)

oipA"on"

68(91.9)

71(91)

41(89.1)

30(90.9)

27(71.1)

237(88.1)

oipA"off"

3(4.1)

2(2.6)

0

0

0

5(1.9)

dupA

23(31.1)

12(15.4)

34(73.9)

27(81.8)

25(65.8)

121(45)

  1. Isolates were from five regions of China: Shandong (SD), Guangxi (GX), Hunan (HN), Qinghai (QH) and Heilongjiang (HL)
  2. Values in parentheses are percentages
  3. Numbers in boldface type indicate a significant difference compared with other regions