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Table 3 Frequency of 269 H. pylori virulence genotypes in patients with NUD and PUD

From: Geographic distribution of the cagA, vacA, iceA, oipA and dupA genes of Helicobacter pylori strains isolated in China

Genetypes

No. of isolates

SD (n = 74)

GX (n = 78)

HN (n = 46)

QH (n = 33)

HL (n = 38)

Total (n = 269)

NUD (61)

PUD (13)

NUD (75)

PUD (3)

NUD (42)

PUD (4)

NUD (32)

PUD (1)

NUD (38)

PUD (0)

NUD (248)

PUD (21)

cagA

58(95.1)

12(92.3)

71(94.7)

3(100)

42(100)

4(100)

32(100)

1(100)

38(100)

0

241(97.2)

20(95.2)

vacA

            

 s1

60(98.4)

12(92.3)

75(100)

3(100)

41(97.6)

4(100)

30(93.8)

0

38(100)

0

244(98.4)

19(90.5)

 s2

1(1.6)

1(7.7)

0

0

1(2.4)

0

2(6.6)

1(100)

0

0

4(1.6)

2(9.5)

 m1

26(42.6)

4(30.8)

13(17.3)

1(33.3)

10(23.8)

0

6(18.8)

0

12(31.6)

0

67(27)

5(23.8)

 m2

34(55.7)

9(69.2)

59(78.7)

2(66.7)

31(73.8)

4(100)

25(78.1)

1(100)

25(65.8)

0

174(70.2)

16(76.2)

 i1

56(91.8)

10(76.9)

68(90.7)

3(100)

42(100)

4(100)

29(90.6)

0

38(100)

0

233(94)

17(81)

 i2

5(8.2)

3(23.1)

7(9.3)

0

0

0

3(9.4)

1(100)

0

0

15(6)

4(19)

 s1i1m1

21(34.4)

1(7.7)

11(14.7)

1(33.3)

10(23.8)

0

6(18.8)

0

12(31.6)

0

60(24.2)

2(9.5)

 s1i1m2

33(54.1)

9(69.2)

51(68)

2(66.7)

30(71.4)

4(100)

22(68.8)

0

25(65.8)

0

161(64.9)

15(71.4)

 s1i2m1

5(8.2)

2(15.4)

2(2.7)

0

0

0

0

0

0

0

7(2.8)

2(9.5)

 s1i2m2

0

0

5(6.7)

0

0

0

1(3.1)

0

0

0

6(2.4)

0

 s2i1m1

0

0

0

0

0

0

0

0

0

0

0

0

 s2i1m2

1(1.6)

0

0

0

1(2.4)

0

0

0

0

0

2(0.8)

0

 s2i2m1

0

1(7.7)

0

0

0

0

0

0

0

0

0

1(4.8)

 s2i2m2

0

0

0

0

0

0

3(9.4)

0

0

0

0

0

iceA1

40(65.6)

9(69.2)

48(64)

2(66.7)

35(83.3)

3(75)

23(69.7)

1(100)

26(68.4)

0

172(69.4)

15(71.4)

iceA2

9(14.8)

3(23.1)

19(25.3)

1(33.3)

7(16.7)

1(25)

6(18.2)

0

8(21.1)

0

49(19.8)

5(23.8)

oipA"on"

55(90.2)

13(100)

68(90.7)

3(100)

37(88.1)

4(100)

29(87.9)

1(100)

27(71.1)

0

216(87.1)

21(100)

oipA"off"

3(4.9)

0

2(2.7)

0

0

0

0

0

0

0

5(2)

0

dupA

15(24.6)

8(61.5)

10(13.3)

2(66.7)

32(76.2)

2(50)

26(78.8)

1(100)

25(65.8)

0

108(43.5)

13(61.9)

  1. Isolates were from five regions of China: Shandong (SD), Guangxi (GX), Hunan (HN), Qinghai (QH) and Heilongjiang (HL)
  2. Values in parentheses are percentages
  3. Numbers in boldface type indicate a significant difference compared clinical outcomes (NUD and PUD) in each geographic region group with respect to H. pylori genotype