Table 4 Diagnostic performance of the 13C-UBT and 14C-UBT with optimal H. pylori-positive and -negative cutoff values, and the inclusion of an indeterminate range
Method | Histology | Sens (%) 95%CI | Spec (%) 95%CI | Acc (%) 95%CI | FPR (%) 95%CI | FNR (%) 95%CI | ||
|---|---|---|---|---|---|---|---|---|
+ | – | |||||||
13C-UBT | + (≥ 10.4%) | 120 | 14 | 96 90.4–98.5 | 76.7 63.7–86.2 | 89.7 84.5–93.4 | 23.3 13.8–36.3 | 4 1.5–9.6 |
− (≤ 2.9%) | 5 | 46 | ||||||
IND (3–10.3%) | 18 | 14 | ||||||
14C-UBT | + (≥ 238 DPM) | 158 | 12 | 98.1 94.2–99.5 | 76.9 62.8–87.0 | 93 88.6–95.8 | 23.1 13.0–37.2 | 1.9 0.5–5.8 |
− (≤ 86 DPM) | 3 | 40 | ||||||
IND (87–237 DPM) | 31 | 23 | ||||||