Table 2 Reported mutations in the PBP1A binding site and tunnel-1 residues of AMX-resistant and susceptible strains

From: The penicillin binding protein 1A of Helicobacter pylori, its amoxicillin binding site and access routes

Mutations	Binding site	Tunnel-1	No of strains R¹/S²	Ref
Ala369Thr	✓	✓	3/4^R–0/12^S	[28]
Thr541Ilu	✓	–	1/3^R–0/9^S	[18]
Asn560Thr	✓	✓	1/4^R–0/5^S	[23]
Thr556Ser	✓	–	8/12^R–0/19^S	[16] [18] [23] [29] This study
Phe366Leu	–	✓	7/7^R	[15]
Ser414Arg	✓	✓	31/104^R–1/106^S	[15] [18] [22] [28] [39] This study
Val469Met	–	✓	2/5^R–0/11^S	[24] This study

¹Resistant
²Sensitive

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ISSN: 1757-4749

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