Virulence among different types of hypervirulent Klebsiella pneumoniae with multi-locus sequence type (MLST)-11, Serotype K1 or K2 strains

Table 2 Serotype, MLST and virulence-associated gene detection of the isolates in this study

No. of strains	Serotype	MLST	Virulence gene profiles						Serum resistance: (R, I, S)^a	LD₅₀ (CFU range)
			clb	entB	iroN	iucA	iutA	rmpA
6	K1	23	+	+	+	+	+	+	R	> 2 × 10²–< 2 × 10³
2	K2	65	+	+	+	+	+	+	R	< 10²–2.4 × 10²
1	K2	65	−	+	+	+	+	+	R	< 4 × 10²
2	K2	86	−	+	+	+	+	+	R	< 7.3 × 10²
1	K2	373	−	+	+	+	+	+	R	< 1 × 10²
6	K20	11	−	+	+	+	+	+	S	> 10⁷
5	K47	11	−	+	−	−	−	−	S	> 10⁷
5	K64	11	−	+	−	−	−	−	S	> 10⁷
5	K64	11	−	+	−	−	+	−	S	> 10⁷

^aR resistance, I intermediate resistance, S susceptible. Serum resistance was graded according to the method described in the materials and methods

ISSN: 1757-4749