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Table 5 Characteristics of colistin resistant strains

From: Antibiotic resistance and detection of plasmid mediated colistin resistance mcr-1 gene among Escherichia coli and Klebsiella pneumoniae isolated from clinical samples

Characteristics

Escherichia coli

Klebsiella pneumoniae

Number of isolates tested

179

20

Colistin resistant by MIC determination

4 (2.2%)

2 (10%)

Specimen types of colistin resistant bacteria

Urine for all isolates

Urine for all isolates

In-patient/out-patient

Inpatient- 2

Outpatient- 2

Inpatient- 2

Colistin resistance (MIC µg/ml)

4 µg/ml-3

8 µg/ml-1

8 µg/ml-1

16 µg/ml-1

mcr-1 plasmid detected in colistin resistant

3

0

mcr-1 chromosome detected in colistin resistant

2

0

mcr-1 both plasmid and chromosome detected in colistin resistant

2

0

ESBL producer

2

2

Carbapenem resistance isolates

1

1

MBL producer

1

1

KPC producer

0

0

Isolates with MIC break-point (2 µg/ml) (colistin sensitive)

18

0

mcr-1 plasmid detected in colistin sensitive

5

0

mcr-1 chromosome detected in colistin sensitive

12

0

mcr-1 both plasmid and chromosome detected in colistin sensitive

3

0