In silico molecular docking and in vitro antimicrobial efficacy of phytochemicals against multi-drug-resistant enteroaggregative Escherichia coli and non-typhoidal Salmonella spp.

Table 3 Binding affinity values of tested phytochemicals to dispersin and osmoporin (OmpC) proteins of EAEC and NTS

Sl. No.	Phytochemicals	EAEC			NTS
Sl. No.	Phytochemicals	Binding energy (kcal/mol)	Ligand efficiency	Inhibition constant (µM)	Binding energy (kcal/mol)	Ligand efficiency	Inhibition constant (µM)
1.	Carvacrol	− 5.27	− 0.48	137.22	− 4.49	− 0.41	510.49
2.	Cinnamaldehyde	− 5.65	− 0.57	71.61	− 4.65	− 0.47	390.26
3.	Thymol	− 4.97	− 0.45	227.5	− 4.97	− 0.45	226.89

ISSN: 1757-4749