Fig. 3

Antibiotic treatment reversed the difference in the host susceptibility of WT and Dock2^−/− mice to C. rodentium infection. A Schematic diagram of antibiotic treatment experiments. WT and Dock2^−/−mice were infected with C. rodentium after 4 weeks of antibiotic treatment. Feces were collected on days 5 (B), 10 (C), and 17 (D) for C. rodentium load testing. At day 5, WT, n = 7; WT + Antibiotics, n = 4; Dock2^−/−, n = 6; Dock2^−/−+Antibiotics, n = 5. At day10, WT, n = 5; WT + Antibiotics, n = 4; Dock2^−/−, n = 5; Dock2^−/−+Antibiotics, n = 4. At day17, WT n = 5; WT + Antibiotics n = 4; Dock2^−/− n = 3; Dock2^−/−+Antibiotics n = 3. ** p < 0.01, *** p < 0.001, **** p < 0.0001 vs. WT. Data were presented as mean ± SEM. Results were representative of two independent experiments