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Fig. 6 | Gut Pathogens

Fig. 6

From: Interaction between PSMD10 and GRP78 accelerates endoplasmic reticulum stress-mediated hepatic apoptosis induced by homocysteine

Fig. 6

A proposed model of miRNA expression regulation in HHcy-induced liver injury. Under the condition of hyperhomocysteinemia (HHcy), down-regulated miR-212-5p specifically upregulates PSMD10 expression in hepatocytes. PSMD10 then activates ER stress through interacting with GRP78 and facilitates apoptosis of hepatocytes, by which Hcy induces liver injury

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Gut Pathogens

ISSN: 1757-4749