Fig. 1
From: Hepatitis D: challenges in the estimation of true prevalence and laboratory diagnosis
HDV virion and nucleic acid structure diagram. A HDV virion has a ribonucleoprotein (RNP) complex inside and an HBV derived envelope outside. The RNP consists of the HDV genome and two isoforms of hepatitis D antigen (HDAg), L-HDAg and S-HDAg. B Structure of HDV RNA. Both genome and antigenome form an unbranched rod-like structure of 1700 bp containing a self-cleaving ribozyme (green boxs). The gray box represents HDAg ORF. Arrows on the RNA strands indicate the 5′–3′ direction. HDV hepatitis D virus; L-HDAg large hepatitis D antigen; S-HDAg small hepatitis D antigen