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Table 3 Association between components of sarcopenia and H. pylori markers in normal, H. pylori (+), and CagA (+) groups

From: Detrimental relevance of Helicobacter pylori infection with sarcopenia

Normal Model 1 Model 2 Model 3 Model 4
Ref Ref Ref Ref
Skeletal muscle index (kg/m2)
 H. pylori (+)§     
  β coefficient − 0.015 (− 0.022, − 0.009) − 0.021 (− 0.027, − 0.016) − 0.023 (− 0.028, − 0.018) − 0.023 (− 0.029, − 0.018)
  P value < 0.001 < 0.001 < 0.001 < 0.001
 CagA (+)     
  β coefficient − 0.014 (− 0.022, − 0.007) − 0.016 (− 0.022, − 0.009) − 0.017 (− 0.023, − 0.011) − 0.017 (− 0.023, − 0.011)
  P value < 0.001 < 0.001 < 0.001 < 0.001
Gait speed (m/s)
 H. pylori (+)     
  β coefficient 0.019 (− 0.006, 0.043) 0.013 (− 0.010, 0.036) 0.009 (− 0.013, 0.032) 0.010 (− 0.013, 0.033)
 P value 0.132 0.266 0.417 0.385
  CagA (+)     
  β coefficient 0.014 (− 0.030, 0.058) 0.029 (− 0.013, 0.071) 0.027 (− 0.015, 0.069) 0.027 (− 0.015, 0.069)
  P value 0.536 0.181 0.209 0.206
  1. Model 1 = unadjusted
  2. Model 2 = Adjusted for age, gender, race
  3. Model 3 = Adjusted for age, gender, race, BMI, serum C-reactive protein, serum glucose
  4. Model 4 = Adjusted for age, gender, race, BMI, serum C-reactive protein, serum glucose, smoking, arthritis, asthma, diabetes mellitus
  5. Normal: without evidence of positive anti-H. pylori IgG or anti-CagA IgG
  6. §H. pylori (+): positive anti-H. pylori IgG in serum samples
  7. CagA (+): concurrent positive anti-cytotoxin-associated gene A IgG and positive anti-H. pylori IgG in serum samples