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Fig. 3 | Gut Pathogens

Fig. 3

From: Myxopyronin B inhibits growth of a Fidaxomicin-resistant Clostridioides difficile isolate and interferes with toxin synthesis

Fig. 3

Differential abundance of selected proteins potentially associated with antibiotic tolerance in C. difficile after Rifaximin, Fidaxomicin and Myxopyronin B stress. Averaged relative protein intensities of three biological replicates of each individual protein are displayed and significant changes according to DEqMS analysis are indicated by a *. A Proteins of the CD630_08470-CD630_08500 operon were induced in response to Fidaxomicin and to lesser extent to Myxopyronin B. B and C Two ABC transport system annotated as multidrug resistance efflux systems were induced in response to all three antibiotics. DMSO DMSO-treated samples, Rif Rifaximin-treated samples, Fid Fidaxomicin-treated samples, MyxB Myxopyronin B-treated samples

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Gut Pathogens

ISSN: 1757-4749