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Table 3 Age-stratified relationship between BMI and 30 day mortality among hospitalized patients with CDI, after adjusting for other factors

From: Obesity is not associated with adverse outcomes among hospitalized patients with Clostridioides difficile infection

  Age strata
Age 18–55 Age 56–75 Age > 75
Cochran-armitage p for trend
 BMI (per category increase)a 0.33 0.14 0.37
Adjusted odds ratios and 95% confidence intervals
 BMI categories
  BMI < 20 0.89 (0.27–2.63) 0.50 (0.19–1.17) 0.56 (0.23–1.27)
  BMI 20–25 Reference Reference Reference
  BMI 25–30 0.86 (0.31–2.27) 0.85 (0.50–1.43) 0.85 (0.47–1.53)
  BMI 30–35 1.12 (0.36–3.19) 0.69 (0.35–1.30) 1.04 (0.44–2.33)
  BMI 35–40 4.58 (1.20–16.06) 0.90 (0.38–1.95) 0.23 (0.01–1.30)
  BMI 40–45 1.10 (0.06–7.03) 1.04 (0.31–2.96) 0.68 (0.03–5.34)
  BMI > 45 1.19 (0.16–5.48) 1.36 (0.41–4.01)
  1. Odds ratios adjusted for Charlson comorbidity index, increased serum creatinine, low albumin, increased WBC count, ICU stay, abnormal heart rate, abnormal MAP, abnormal platelet count, and abnormal total bilirubin
  2. BMI, body mass index; WBC, white blood cell; ICU, intensive care unit; MAP, mean arterial pressure
  3. aThe Cochran-Armitage test was used to assess trend across BMI categories (same categories as specified in table)