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Fig. 4 | Gut Pathogens

Fig. 4

From: Virulence genes expression profiling of different Shigella flexneri serotypes in response to sub-inhibitory concentrations of azithromycin and ciprofloxacin

Fig. 4

Diversity in transcriptional profiles of S. flexneri virulence genes in response to sublethal concentrations of antibiotics. Transcriptional profiles of invasion plasmid antigen (ipa) B, intracellular movement (ics) A, virulence factor production (vir) B and intracellular movement (ics) B genes of S. flexneri serotypes 4a, 3a and 2a after treatment with sub-MIC concentration of A azithromycin (32 µg/mL) or B ciprofloxacin (4 µg/mL) in HT-29 cell line. Expression levels of all genes were normalized to the levels of 16S rRNA gene transcripts, and the folds of expression change were calculated using the relative comparison method (2−ΔΔct, RQ). Results shown are the mean ± std of two independent experiments

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Gut Pathogens

ISSN: 1757-4749