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Fig. 5 | Gut Pathogens

Fig. 5

From: Antimicrobial resistance patterns and genetic elements associated with the antibiotic resistance of Helicobacter pylori strains from Shanghai

Fig. 5

Distribution and constitution of CRISPRs in resistant and susceptible categories and a previously unknown CRISPRs combination present exclusively in seven MTZ mono-R strains. The proportions of strains with 0, 1, 2, 3 and 4 CRISPRs in resistant and susceptible categories of MTZ (A), CLA (B) and LEV (C), respectively. **P < 0.01, n.s. not significant. The proportions of CRISPRs with 1, 2, 3, 4 and 6 spacers in resistant and susceptible categories of MTZ (D), CLA (E) and LEV (F), respectively. *P < 0.05, n.s. not significant. G The structural analysis of a previously unknown CRISPRs combination presented exclusively in seven MTZ mono-R strains, including DRs (purple, yellow and red diamonds in each CRISPR) and spacers (grey, blue and black rectangles in each CRISPR). The base sequences are shown below the CRISPR array. The DRs and spacers in the colored characters correspond with the colors of the respective diamonds and rectangles. The DR sequence in box, which exclusively presented in nine MTZ-R strains, indicated that there was a significant difference of the DR frequencies between MTZ-R and MTZ-S categories. *P < 0.05

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