From: Establishment of a gnotobiotic pig model of Clostridioides difficile infection and disease
Treatment group | n | % affected (%) | Diarrhea onset (mean days) | Diarrhea duration (mean days PID 0–5) | Mean cumulative diarrhea score PID 0–5 | Mean daily weight gain from PID 0–5 | Total weight gain from PID 0–5a | Average weight at PID 5 (kg) | n | Mean days with diarrhea PID 0–10 | Mean cumulative diarrhea score PID 0–10 | Mean daily weight gain from PID 0–10 | Total weight gain from PID 0–10 | Average weight at PID 10 (kg) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C. difficile infected | 5 | 100 | 2.6 (0.24)b | 3.0 (0.55)Ac | 9.4 (1.4)A | 0.02 (0.10)A | 0.1 | 1.6 | 2 | 8.5 (0.35)A | 26 (0.71)A | 0.09 (0.05)A | 0.1 | 1.9 |
Mock-infected control | 4 | 0 | N/A | 0 (0)B | 0.75 (0.75)B | 0.10 (0.05)A | 0.5 | 2 | 2 | 0 (0)B | 2.5 (1.77)B | 0.01 (0.09)B | 0.9 | 2.3 |