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Table 2 An overview of the metabolomic analysis outcome

From: The gut metagenomics and metabolomics signature in patients with inflammatory bowel disease

Key metabolomics analysis results
Total metabolites identified 3146
Comparative analysis of differences between groups
Groups Total differential metabolites Significant difference metabolic pathways
IBD vs healthy controls 135 Vitamin digestion and absorption, primary bile acid biosynthesis, protein digestion and absorption, ABC transporters, basal cell carcinoma, glutathione metabolism, ferroptosis
AUC aggregate measure of performance of differential metabolites
Metabolite AUC value
6,7,4′-trihydroxyisoflavone 0.92
Thyroxine 4′-o-.beta.-d-glucuronide 0.92
Trichostachine 0.91
[(2r,3 s,4 s,5r,6r)-3,4,5-trihydroxy-6-[2-(3-hydroxy-5-oxooxolan-3-yl)propoxy]oxan-2-yl]methyl (e)-3-(3,4-dihydroxyphenyl)prop-2-enoate 0.91
Normorphine 0.90
Salvinorin a 0.90
Esculetin 0.89
Mitraphylline 0.88
Indole-3-carboxaldehyde 0.88
Ginsenoside rh2 0.88
Arachidonoylserotonin 0.88
11-hydroxy-5z,8z,12e,14z,17z-eicosapentaenoic acid 0.88
10-deacetylbaccatin iii 0.88
9-cis-retinol 0.88
(5-benzoyloxy-3-chloro-4,6-dihydroxycyclohexen-1-yl)methyl benzoate 0.88
[(4e)-7-acetyloxy-6-hydroxy-2-methyl-10-oxo-2,3,6,7,8,9-hexahydrooxecin-3-yl] (e)-but-2-enoate 0.87
Dihydroberberine 0.87
N-nitrosopyrroolidine 0.87
Prothioconazole 0.87
Patchouli alcohol 0.87