Skip to main content

Table 3 Dysregulated KEGG metabolic pathways and associated metabolites in IBD

From: The gut metagenomics and metabolomics signature in patients with inflammatory bowel disease

Pathway hierarchy Map ID Map name Metabolite name Up number Down number
Digestive system hsa04977 Vitamin digestion and absorption Flavin mononucleotide (fmn), Pantothenate, Thiamine, ( +)-.alpha.-tocopherol, Cholesterol 1 4
Digestive system hsa04974 Protein digestion and absorption L-Valine, Isovaleric acid, Glutamic acid, DL-tyrosine, DL-Glutamic acid 1 4
Lipid metabolism hsa00120 Primary bile acid biosynthesis Cholic acid, 25-hydroxycholesterol, 7.alpha., 27-dihydroxycholesterol|Cholesterol 1 3
Cell growth and death hsa04216 Ferroptosis Glutamic acid, ( +)-.alpha.-tocopherol, DL-Glutamic acid, L-glutathione, reduced 1 3
Membrane transport hsa02010 ABC transporters L-Valine, Glycerol, Glutamic acid, Deoxyinosine|2′-deoxyinosine, Thiamine, DL-Glutamic acid, His-Lys, L-glutathione, reduced 3 6
Metabolism of cofactors and vitamins hsa00770 Pantothenate and CoA biosynthesis L-Valine, Uracil, Pantothenate 1 2
Metabolism of cofactors and vitamins hsa00730 Thiamine metabolism Thiamine monophosphate, DL-tyrosine, Thiamine 1 2
Cancer: overview hsa05230 Central carbon metabolism in cancer L-Valine, Glutamic acid, DL-tyrosine, DL-Glutamic acid 1 3
Metabolism of other amino acids hsa00480 Glutathione metabolism Glutamic acid, 5-L-Glutamyl-L-alanine, DL-Glutamic acid, L-glutathione, reduced 1 3