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Table 1 Clinicopathologic characteristics in F. nucleatum-negative vs. F. nucleatum-positive ALF

From: Fusobacterium nucleatum promotes the development of acute liver failure by inhibiting the NAD+ salvage metabolic pathway

Characteristics

F.nucleatum-negative (n = 15)

F.nucleatum-positive(n = 15)

p valuea

Gender

 Male

6

9

0.126

 Female

9

6

Age

  ≤ 16

0

1

0.505

  ≤ 40

11

7

  > 40

4

7

Clinical course

 Moderate

11

2

0.035*

 Severe

2

13

 Remission

2

0

 PT activity (75% ~ 135%)

35% ± 5

20% ± 5

 Total bilirubin (0 ~ 23 μmol/L)

200 ± 30

350 ± 50

 Procalcitonin (< 0.1 ng/mL)

0.5 ± 0.2

0.8 ± 0.2

 HEV-IgG (0 ~ 1)

17 ± 3

14 ± 5

 AST (15 ~ 40U/L)

3150 ± 150

3850 ± 200

 ALT (9 ~ 50U/L)

3230 ± 300

3450 ± 150

Behavior

 B1

7

5

0.495

 B2

5

4

 B3

3

6

Surgery

 Yes

3

11

0.017*

 No

12

4

  1. aChi-square test, *P < 0.05