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Fig. 10 | Gut Pathogens

Fig. 10

From: Amoxicillin modulates gut microbiota to improve short-term high-fat diet induced pathophysiology in mice

Fig. 10

Impact of high-fat diet (3 weeks) and amoxicillin treatment on anti-bacterial activity of macrophages against S. aureus and A. baumannii. CFU recovery from peritoneal macrophages isolated from mice fed on different diets: Data represents mean ± SEM, One-way ANOVA followed by Bonferroni post-hoc test. p ≤ 0.05, NS=  not significant. CFU recovery of (a) S. aureus, and (b) A. baumannii at times 0, 2, 4, and 8 h (hrs) post-infection. There is no significant difference in CFU across the groups indicating that amoxicillin treatment does not significantly impair cell’s susceptibility and ability to clear microbial infections. All experiments were performed in triplicates. CD: Standard-chow diet for 3 weeks; CD + Amox: Standard-chow diet for 3 weeks and subjected to amoxicillin treatment  in 3rd week; HFD: High-fat diet for 3 weeks; HFD + Amox: High-fat diet for 3 weeks and subjected to amoxicillin treatment in 3rd week

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