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Fig. 4 | Gut Pathogens

Fig. 4

From: Metagenomic analysis of the interaction between the gut microbiota and colorectal cancer: a paired-sample study based on the GMrepo database

Fig. 4

A Volcano plot. The log2-fold-change indicates the mean relative abundance for each species. Each dot represents one species. The grey dots represent species with no significant expression difference or species with |log2 Fold-Change|≤ 1.0 (CRC versus controls), the red dots represent depleted taxa in CRC groups compared with controls, and the light blue dots represent enriched taxa. The Wilcoxon-signed rank test was performed, and p < 0.05 was considered statistically significant. B Venn diagrams illustrating the number of species identified by the primary random forest model, including the top 50 microbial markers (pink) and the 44 species by the Wilcoxon signed rank test (light blue). C The paired scatter plot of the 14 commonly identified species between CRC and controls. D The area under the curve (AUC) of different models. CRC: colorectal cancer; Sens: sensitivity, Spec: specificity

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