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Fig. 5 | Gut Pathogens

Fig. 5

From: Association of gut microbial dysbiosis with disease severity, response to therapy and disease outcomes in Indian patients with COVID-19

Fig. 5

Heatmap of bacterial gene functional prediction using the latest PICRUSt2 algorithm from the faecal samples of Indian COVID-19 patients

Using the amplicon sequence variants (ASV) and the biome table generated from QIIME2 database as input, PICRUSt2 predicted the KEGG-level pathways. The relative abundance was then calculated from the observed abundance of each pathway in each sample. In mild and severe COVID-19 patients a total of 23 metabolic pathways were statistically significant between the groups (p-value < 0.05, Mann Whitney U test). Among these 23 metabolic pathways, 12 were found to be highly upregulated in mild patients (p-value < 0.05, Mann Whitney U test)

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Gut Pathogens

ISSN: 1757-4749