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Fig. 6 | Gut Pathogens

Fig. 6

From: Association of gut microbial dysbiosis with disease severity, response to therapy and disease outcomes in Indian patients with COVID-19

Fig. 6

Association between gut bacteria and plasma cytokine levels in mild and severe patients

(A) The co-occurrence among the significantly different genera and cytokines was calculated using Spearman’s rank correlation coefficient (ρ) in Mild patients.The relative abundance of the genera and log fold change (absolute values) were used for the calculation and threshold was set to r > 0.5. All calculations were done using R package, function cor(). The nodes represent genera and cytokines which are colourencoded. Green nodes represent cytokines and the blue nodes represent genera. The edges represent strong positive interaction between cytokine and genera. (B) Circos plot representing the co-occurrence among the significantly different genera and cytokinesin severe COVID-19 patients calculated using Spearman’s rank correlation coefficient (ρ) with the threshold set to r > 0.4. Only positive associations crossed the threshold cut-off and are represented in green where a darker shade represents stronger correlation.

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