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  1. The urea breath test (UBT) is widely used for diagnosing Helicobacter pylori infection. In the Shenzhen Kuichong People’s Hospital, some UBT findings were contradictory to the histology outcomes, therefore this s...

    Authors: Xiangyu Wang, Shuzhen Zhang, Eng Guan Chua, Yongsheng He, Xiaofeng Li, Aijun Liu, Haiting Chen, Michael J. Wise, Barry J. Marshall, Dayong Sun, Xuehong Li and Chin Yen Tay

    Citation: Gut Pathogens 2021 13:38

    Content type: Research

    Published on:

  2. The classification of natural antimicrobials as potential antibiotic replacements is still hampered by the absence of clear biological mechanisms behind their mode of action. This study investigated the mechan...

    Authors: Igori Balta, Adela Marcu, Mark Linton, Carmel Kelly, Ozan Gundogdu, Lavinia Stef, Ioan Pet, Patrick Ward, Myriam Deshaies, Todd Callaway, Phittawat Sopharat, Gratiela Gradisteanu-Pircalabioru and Nicolae Corcionivoschi

    Citation: Gut Pathogens 2021 13:37

    Content type: Research

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  3. Even though the incidence of H. pylori infection among Malays in the Malay Peninsula is low, we observed a high H. pylori prevalence in Sumatra, which is the main residence of Indonesian Malays. H. pylori prevale...

    Authors: Ari Fahrial Syam, Langgeng Agung Waskito, Yudith Annisa Ayu Rezkitha, Rentha Monica Simamora, Fauzi Yusuf, Kanserina Esthera Danchi, Ahmad Fuad Bakry, Arnelis, Erwin Mulya, Gontar Alamsyah Siregar, Titong Sugihartono, Hasan Maulahela, Dalla Doohan, Muhammad Miftahussurur and Yoshio Yamaoka

    Citation: Gut Pathogens 2021 13:36

    Content type: Research

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  4. Non-typhoidal salmonellosis remains a pressing public health problem worldwide. Quinolones, particularly fluoroquinolones, are widely used to treat various infections, including non-typhoidal salmonellosis, wh...

    Authors: Sohyun Lee, Nanjoo Park, Sujung Yun, Eunseon Hur, Jiwon Song, Hanna Lee, Yongsug Kim and Sangryeol Ryu

    Citation: Gut Pathogens 2021 13:35

    Content type: Letter to the Editor

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  5. Norovirus genotype GII.3[P12] strains have been an important pathogen for sporadic gastroenteritis infection. In previous studies of GII.3[P12], the number of specimens and time span are relatively small, whic...

    Authors: Jianguang Fu, Jing Ai, Changjun Bao, Jun Zhang, Qingbin Wu, Liguo Zhu, Jianli Hu and Zheng Xing

    Citation: Gut Pathogens 2021 13:34

    Content type: Research

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  6. Diarrhea remains the leading cause of childhood illness in China. Better understanding of burden and etiology of diarrheal diseases is important for development of effective prevention measures.

    Authors: Hong-Lu Zhou, Theresa Bessey, Song-Mei Wang, Zhao-Jun Mo, Leslie Barclay, Jin-Xia Wang, Can-Jing Zhang, Jing-Chen Ma, Chao Qiu, Gan Zhao, Rong-Cheng Li, Yu-Liang Zhao, Baoming Jiang and Xuan-Yi Wang

    Citation: Gut Pathogens 2021 13:33

    Content type: Research

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  7. Although Escherichia coli is the most frequently isolated microorganism in acute biliary tract infections with bacteremia, data regarding its virulence are limited.

    Authors: Mahoko Ikeda, Tatsuya Kobayashi, Fumie Fujimoto, Yuta Okada, Yoshimi Higurashi, Keita Tatsuno, Shu Okugawa and Kyoji Moriya

    Citation: Gut Pathogens 2021 13:32

    Content type: Research

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  9. Mycobacterium avium subspecies paratuberculosis (MAP), the cause of Johne disease, is a slow growing mycobacterium. Viable MAP detection is difficult, inconstant and time-consuming. The purpose of this study was ...

    Authors: Robert J. Greenstein, Liya Su, Irene R. Grant, Antonio C. G. Foddai, Amy Turner, Jason S. Nagati, Sheldon T. Brown and Judith R. Stabel

    Citation: Gut Pathogens 2021 13:30

    Content type: Research

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  10. By 27 June 2020, almost half a million people had died due to COVID-19 infections. The susceptibility and severity of infection vary significantly across nations. The contribution of chronic viral and parasiti...

    Authors: Enas Fakhry Abdel-Hamed, Mohamed N. Ibrahim, Nahed E. Mostafa, Howayda S. F. Moawad, Nahla E. Elgammal, Ehab M. Darwiesh, Dina S. El-rafey, Nissreen E. ElBadawy, Emad Ali Al-Khoufi and Salwa I. Hindawi

    Citation: Gut Pathogens 2021 13:29

    Content type: Research

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  11. Poor self-care skills and personal hygiene resulted from limitations in learning and understanding, put intellectually disabled individuals at greater risk for intestinal parasitic infections (IPIs). Despite s...

    Authors: Mohammad Javad Abbaszadeh Afshar, Mehdi Mohebali, Sina Mohtasebi, Aref Teimouri, Bahareh Sedaghat and Reza Saberi

    Citation: Gut Pathogens 2021 13:28

    Content type: Review

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  12. Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) is an important zoonotic agent worldwide. The aim of this work was to compare genetically 117 S. Typhimurium isolated from different source...

    Authors: Amanda Ap. Seribelli, Patrick da Silva, Marcelo Ferreira da Cruz, Fernanda de Almeida, Miliane R. Frazão, Marta I. C. Medeiros, Dália dos P. Rodrigues, Jalusa D. Kich, Leandro de Jesus Benevides, Siomar de C. Soares, Marc W. Allard and Juliana Pfrimer. Falcão

    Citation: Gut Pathogens 2021 13:27

    Content type: Research

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  13. Helicobacter cinaedi are motile, gram-negative spiral rods with a natural reservoir in the intestinal tract of hamsters and rhesus monkeys. In humans, H. cinaedi has been reported in different human infections li...

    Authors: Sofie Larsen Rasmussen, Iben Ørsted, Irene Harder Tarpgaard and Hans Linde Nielsen

    Citation: Gut Pathogens 2021 13:26

    Content type: Case report

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  14. Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease after Alzheimer's disease (AD) worldwide. The prevalence of small intestinal bacterial overgrowth (SIBO) in PD patients is high. ...

    Authors: Xiaoqing Li, Xin Feng, Zhongxiang Jiang and Zheng Jiang

    Citation: Gut Pathogens 2021 13:25

    Content type: Review

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  15. Cytomegalovirus (CMV)-associated gastrointestinal diseases usually occur in immunocompromised patients; however, few cases has also been described in healthy hosts despite still unclear pathological mechanisms...

    Authors: Daisuke Murakami, Hideaki Harada, Masayuki Yamato and Yuji Amano

    Citation: Gut Pathogens 2021 13:24

    Content type: Case report

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  16. The cytotoxin-associated gene A (cagA) is one of the most important virulence factors of Helicobacter pylori (H. pylori). There is a highly polymorphic Glu-Pro-Ile-Tyr-Ala (EPIYA) repeat region in the C-terminal ...

    Authors: Zhijing Xue, Yuanhai You, Lihua He, Yanan Gong, Lu Sun, Xiurui Han, Ruyue Fan, Kangle Zhai, Yaming Yang, Maojun Zhang, Xiaomei Yan and Jianzhong Zhang

    Citation: Gut Pathogens 2021 13:23

    Content type: Research

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  17. Interferon-alpha (IFN-α) and nucleot(s)ide analogs (NAs) are first-line drugs for the treatment of chronic hepatitis B virus (HBV) infections. Generally, NAs target the reverse transcription of HBV pregenomic ...

    Authors: Gang Wang, Jun Guan, Nazif U. Khan, Guojun Li, Junwei Shao, Qihui Zhou, Lichen Xu, Chunhong Huang, Jingwen Deng, Haihong Zhu and Zhi Chen

    Citation: Gut Pathogens 2021 13:22

    Content type: Review

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  18. Rotavirus (RV) is a leading cause of pediatric diarrhea and mortality worldwide. The virus causes acute gastroenteritis characterized by moderate to severe vomiting, diarrhea, dehydration, and fever. Microbial...

    Authors: Muhammad U. Sohail, Hebah A. Al Khatib, Asmaa A. Al Thani, Khalid Al Ansari, Hadi M. Yassine and Maha Al-Asmakh

    Citation: Gut Pathogens 2021 13:21

    Content type: Short Report

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  19. One of the approaches to cure human immunodeficiency virus (HIV) is the use of therapeutic vaccination. We have launched the Provir/Latitude 45 study to identify conserved CTL epitopes in archived HIV-1 DNA ac...

    Authors: Patricia Recordon-Pinson, Annie Gosselin, Petronela Ancuta, Jean-Pierre Routy and Hervé Fleury

    Citation: Gut Pathogens 2021 13:20

    Content type: Short report

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  20. Colorectal cancer (CRC) is one of the top ten causes of cancer deaths in the world. Despite an increased prevalence of colorectal cancer has been documented from developing countries, there is no any report re...

    Authors: Yesuf Adem Siraj, Melesse Gebeyehu Biadgelign, Mensur Osman Yassin and Yohannes Zenebe Chekol

    Citation: Gut Pathogens 2021 13:19

    Content type: Research

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  21. Infections caused by multidrug-resistant shigellae resistant to broad-spectrum cephalosporins are becoming more prevalent in the Middle East. We report a case of severe diarrhea due to a multiresistant Shigella f...

    Authors: M. John Albert, Prashant Purohit, Laurent Poirel, Glen Carter and Dieter Bulach

    Citation: Gut Pathogens 2021 13:18

    Content type: Case report

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  22. Spontaneous bacterial peritonitis (SBP) is one of the most common infectious diseases in patients with cirrhosis and is associated with serious prognosis. A prevailing dogma posits that SBP is exacerbated by t...

    Authors: Saad Alhumaid, Abbas Al Mutair, Zainab Al Alawi, Abdul Rehman Zia Zaidi, Ali A. Rabaan, Alyaa Elhazmi and Awad Al-Omari

    Citation: Gut Pathogens 2021 13:17

    Content type: Research

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  23. Alteration in the gut microbiota has been proposed in irritable bowel syndrome (IBS) pathogenesis, especially in the diarrheal type (IBS-D). We conducted this study to evaluate the fecal microbiota in Thai IBS...

    Authors: Sawangpong Jandee, Suppana Chuensakul and Suppasil Maneerat

    Citation: Gut Pathogens 2021 13:16

    Content type: Research

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  24. The membrane fusion protein (mfp) gene locus of Vibrio parahaemolyticus consists of two operons, cpsQ-mfpABC and mfpABC, which are both required for biofilm formation. ToxR and CalR are required for the full viru...

    Authors: Yiquan Zhang, Yue Qiu, Xingfan Xue, Miaomiao Zhang, Junfang Sun, Xue Li, Lingfei Hu, Zhe Yin, Wenhui Yang, Renfei Lu and Dongsheng Zhou

    Citation: Gut Pathogens 2021 13:15

    Content type: Research

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  25. COVID-19 is an acute respiratory distress syndrome and is often accompanied by gastrointestinal symptoms. The SARS-CoV-2 has been traced not only in nasopharyngeal and mid-nasal swabs but also in stool and rec...

    Authors: Jyoti Chhibber-Goel, Sreehari Gopinathan and Amit Sharma

    Citation: Gut Pathogens 2021 13:14

    Content type: Commentary

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  26. This study aims to characterize, the gut and oral microbiome in Asian subjects with Crohn’s disease (CD) using whole genome shotgun sequencing, thereby allowing for strain-level comparison.

    Authors: Shijia Hu, Eileen Png, Michelle Gowans, David E. H. Ong, Paola Florez de Sessions, Jie Song and Niranjan Nagarajan

    Citation: Gut Pathogens 2021 13:13

    Content type: Research

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  27. The aim of this study was to determine the dominant species of bacteria found in blood cultures collected from patients under treatment in the tertiary inflammatory bowel disease (IBD) center in Poland. The do...

    Authors: Jolanta Gruszecka and Rafał Filip

    Citation: Gut Pathogens 2021 13:12

    Content type: Letter to the Editor

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  28. Gastric adenocarcinoma is associated with H. pylori infection and inflammation that can result in the dysbiosis of gastric microbiota. The association of intestinal microbiota with gastric adenocarcinoma subtypes...

    Authors: Virinder Sarhadi, Binu Mathew, Arto Kokkola, Tiina Karla, Milja Tikkanen, Hilpi Rautelin, Leo Lahti, Pauli Puolakkainen and Sakari Knuutila

    Citation: Gut Pathogens 2021 13:11

    Content type: Research

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  29. Clostridioides difficile infection (CDI) is a common hospital-associated diarrhea. Several antibiotics commonly associate with CDI; however, limited data are available on the duration of exposure prior to CDI. Mo...

    Authors: Khadijah M. Alammari and Abrar K. Thabit

    Citation: Gut Pathogens 2021 13:10

    Content type: Research

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  30. Shewanella xiamenensis has been reported in water environment and in patients and can act as the originator of oxacillinase in gram-negative bacteria. In order to assess genome plasticity and its functional prope...

    Authors: Thongpan Leangapichart, Linda Hadjadj, Philippe Gautret and Jean-Marc Rolain

    Citation: Gut Pathogens 2021 13:9

    Content type: Genome Report

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  31. Shiga toxin-producing Escherichia coli (STEC) is a pathotype of E. coli that causes enteric and systemic diseases ranging from diarrhoea to severe hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The...

    Authors: Walid Elmonir, Samar Shalaan, Amin Tahoun, Samy F. Mahmoud, Etab M. Abo Remela, Radwa Eissa, Hanem El-Sharkawy, Mustafa Shukry and Rasha N. Zahran

    Citation: Gut Pathogens 2021 13:8

    Content type: Research

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  32. SARS-CoV-2 has been detected not only in respiratory secretions, but also in stool collections. Here were sought to identify SARS-CoV-2 by enrichment next-generation sequencing (NGS) from fecal samples, and to...

    Authors: Andreas Papoutsis, Thomas Borody, Siba Dolai, Jordan Daniels, Skylar Steinberg, Brad Barrows and Sabine Hazan

    Citation: Gut Pathogens 2021 13:7

    Content type: Research

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  33. Bacillus cereus is ubiquitous in nature, found in environments such as soil, plants, air, and part of the insect and human gut microbiome. The ability to produce endospores and biofilms contribute to their pathog...

    Authors: Balakrishnan N. V. Premkrishnan, Cassie E. Heinle, Akira Uchida, Rikky W. Purbojati, Kavita K. Kushwaha, Alexander Putra, Puramadathil Sasi Santhi, Benjamin W. Y. Khoo, Anthony Wong, Vineeth Kodengil Vettath, Daniela I. Drautz-Moses, Ana Carolina M. Junqueira and Stephan C. Schuster

    Citation: Gut Pathogens 2021 13:6

    Content type: Genome Report

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  34. Intestinal fibrosis is a frequent complication of Crohn’s disease. However, the factors that cause chronicity and promote fibrogenesis are not yet understood.

    Authors: Dina Chokr, Marjorie Cornu, Christel Neut, Clovis Bortolus, Rogatien Charlet, Pierre Desreumaux, Silvia Speca and Boualem Sendid

    Citation: Gut Pathogens 2021 13:5

    Content type: Research

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  35. Campylobacter spp. enteritis is the most frequent bacterial enteritis in both adults and children and is sometimes a source of severe complications. Its diagnosis by culture suffers from a lack of sensitivity and...

    Authors: Justine Franco, Lucie Bénejat, Astrid Ducournau, Francis Mégraud, Philippe Lehours and Emilie Bessède

    Citation: Gut Pathogens 2021 13:4

    Content type: Research

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  36. The emerging intestinal pathogen Campylobacter concisus has been associated with prolonged diarrhoea and classic inflammatory bowel diseases (IBD) and was recently also linked with microscopic colitis (MC). Previ...

    Authors: Marta Emilie Yde Aagaard, Karina Frahm Kirk, Henrik Nielsen and Hans Linde Nielsen

    Citation: Gut Pathogens 2021 13:3

    Content type: Short report

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  37. Inflammatory bowel disease caused by microbial dysbiosis is an important factor contributing to colorectal cancer (CRC) initiation. The ‘driver-passenger’ model in human gut microbial dysbiosis suggests that ‘...

    Authors: Yijia Wang, Xuehua Wan, Xiaojing Wu, Chunze Zhang, Jun Liu and Shaobin Hou

    Citation: Gut Pathogens 2021 13:2

    Content type: Research

    Published on:

  38. Colorectal adenomatous polyps (CAPs) are considered precancerous lesions of colorectal cancer (CRC). The gut microbiota participates in the process of digestion and, in the process, produces metabolites, mainl...

    Authors: Ciyan Chen, Min Niu, Junxi Pan, Na Du, Shumin Liu, Huanqin Li, Qiuyue He, Jian Mao, Yong Duan and Yan Du

    Citation: Gut Pathogens 2021 13:1

    Content type: Research

    Published on:

  39. Helicobacter pullorum commonly colonized in the gastrointestinal tract of poultry and caused gastroenteritis. This bacterium could be transmitted to humans through contaminated food and caused colitis and hepatit...

    Authors: Guilan Zhou, Hao Liang, Yixin Gu, Changyan Ju, Lihua He, Pengbo Guo, Zhujun Shao, Jianzhong Zhang and Maojun Zhang

    Citation: Gut Pathogens 2020 12:56

    Content type: Research

    Published on:

  41. The emergence and transmission of the mobile colistin resistance gene (mcr-1) threatened the extensive use of polymyxin antimicrobials. Accumulated evidence showed that the banning of colistin additive in livesto...

    Authors: Cong Shen, Lan-Lan Zhong, Furong Ma, Mohamed Abd El-Gawad El-Sayed Ahmed, Yohei Doi, Guili Zhang, Yang Liu, Songyin Huang, Hong-Yu Li, Liyan Zhang, Kang Liao, Yong Xia, Min Dai, Bin Yan and Guo-Bao Tian

    Citation: Gut Pathogens 2020 12:55

    Content type: Short report

    Published on:

  42. The global emergence of plasmid-mediated colistin resistance (Col-R) conferred by mcr genes in gram-negative rods (GNRs) has jeopardized the last treatment option for multidrug-resistant bacterial infections in h...

    Authors: Humera Javed, Sidrah Saleem, Aizza Zafar, Aamir Ghafoor, Ahmad Bin Shahzad, Hasan Ejaz, Kashaf Junaid and Shah Jahan

    Citation: Gut Pathogens 2020 12:54

    Content type: Research

    Published on:

  43. Cathelicidins are a class of antimicrobial peptide, and the murine cathelicidin-related antimicrobial peptide (mCRAMP) has been demonstrated in vitro to impair Salmonella enterica serovar Typhimurium proliferatio...

    Authors: Danisa M. Bescucci, Sandra T. Clarke, Catherine L. J. Brown, Valerie F. Boras, Tony Montina, Richard R. E. Uwiera and G. Douglas Inglis

    Citation: Gut Pathogens 2020 12:53

    Content type: Research

    Published on:

  44. Quinolone prophylaxis is recommended for patients with advanced cirrhosis at high risk of spontaneous bacterial peritonitis (SBP) or with prior SBP. Yet, the impact of long-term antibiotic prophylaxis on the m...

    Authors: Marcus M. Mücke, Sabrina Rüschenbaum, Amelie Mayer, Victoria T. Mücke, Katharina M. Schwarzkopf, Stefan Zeuzem, Jan Kehrmann, René Scholtysik and Christian M. Lange

    Citation: Gut Pathogens 2020 12:51

    Content type: Research

    Published on:

  45. Increasing evidence demonstrate that the gut microbiota is involved in the pathogenesis of liver diseases, and faecal microbiota transplantation is considered to be a promising new treatment option. However, t...

    Authors: Xiu-An Yang, Fengchun Lv, Ran Wang, Yange Chang, Yiming Zhao, Xinyu Cui, Haochen Li, Sixi Yang, Suting Li, Xuemin Zhao, Zhishuo Mo and Fang Yang

    Citation: Gut Pathogens 2020 12:50

    Content type: Research

    Published on:

  46. The steady increase in the proportion of Non-typhoidal Salmonella (NTS) infections in humans represents a major health problem worldwide. The current study investigated the serovar distribution and antimicrobial ...

    Authors: Jobin John Jacob, Dhanalakshmi Solaimalai, Dhiviya Prabaa Muthuirulandi Sethuvel, Tanya Rachel, Praveena Jeslin, Shalini Anandan and Balaji Veeraraghavan

    Citation: Gut Pathogens 2020 12:49

    Content type: Research

    Published on:

  47. MiR-146a, an effector mediator, targets Notch-1 and regulates the innate and adaptive immune systems response. Recently, we reported that Notch-1 signaling plays a key role in macrophage polarization and respo...

    Authors: Esra’a Keewan and Saleh A. Naser

    Citation: Gut Pathogens 2020 12:48

    Content type: Research

    Published on:

  49. Fusobacterium nucleatum (Fn) is frequently found in colorectal cancers (CRCs). High loads of Fn DNA are detected in CRC tissues with microsatellite instability-high (MSI-H), or with the CpG island hypermethylatio...

    Authors: Yoshiki Okita, Minoru Koi, Koki Takeda, Ryan Ross, Bhramar Mukherjee, Erika Koeppe, Elena M. Stoffel, Joseph A. Galanko, Amber N. McCoy, Temitope O. Keku, Yoshinaga Okugawa, Takahito Kitajima, Yuji Toiyama, Eric Martens and John M. Carethers

    Citation: Gut Pathogens 2020 12:46

    Content type: Letter to the Editor

    Published on:

  50. Based on MLST analyses the global population of C. difficile is distributed in eight clades, of which Clade 2 includes the “hypervirulent” NAP1/RT027/ST01 strain along with various unexplored sequence types (STs)...

    Authors: Josué Orozco-Aguilar, Alejandro Alfaro-Alarcón, Luis Acuña-Amador, Esteban Chaves-Olarte, César Rodríguez and Carlos Quesada-Gómez

    Citation: Gut Pathogens 2020 12:45

    Content type: Research

    Published on:

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  • ISSN: 1757-4749 (electronic)

Gut Pathogens

ISSN: 1757-4749