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  1. Inflammatory bowel disease (comprising ulcerative colitis and Crohn’s disease) is a multifactorial disease that is extensively associated with stool microbiome changes (dysbiosis). Appendicitis and appendectom...

    Authors: Sultan Alkadhi, Dale Kunde, Rajkumar Cheluvappa, Sarron Randall-Demllo and Rajaraman Eri

    Citation: Gut Pathogens 2014 6:25

    Content type: Research

    Published on:

  2. Enteroendocrine cells (EEC) are highly specialized cells producing signalling molecules vital to the normal functions of the gut. Recently, we showed altered protein distribution in Chlamydia infected EEC in vitr...

    Authors: Aldona Dlugosz, Sandra Muschiol, Katherina Zakikhany, Ghazaleh Assadi, Mauro D’Amato and Greger Lindberg

    Citation: Gut Pathogens 2014 6:24

    Content type: Research

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  3. The present study aimed to determine the inhibitory activity of postbiotic produced by L. plantarum using reconstituted media supplemented with different levels of inulin and to select the best combination based ...

    Authors: Karwan Yassen Kareem, Foo Hooi Ling, Loh Teck Chwen, Ooi May Foong and Samsudin Anjas Asmara

    Citation: Gut Pathogens 2014 6:23

    Content type: Short report

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  4. The healthy human intestine is represented by the presence of bacterial communities predominantly belonging to obligate anaerobes; however disparity and dysanaerobiosis in intestinal microflora may lead to the...

    Authors: Sandeep A Walujkar, Dhiraj P Dhotre, Nachiket P Marathe, Parimal S Lawate, Renu S Bharadwaj and Yogesh S Shouche

    Citation: Gut Pathogens 2014 6:22

    Content type: Research

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  5. In Klebsiella pneumoniae liver abscess (KP-LA), K. pneumonia e K2 is the most frequently isolated serotype after K1, but this serotype has been much less studied. In the present study, the molecular types sequenc...

    Authors: Jung-Chung Lin, Tse Hsien Koh, Nelson Lee, Chang-Phone Fung, Feng-Yee Chang, Yu-Kuo Tsai, Margaret Ip and L Kristopher Siu

    Citation: Gut Pathogens 2014 6:21

    Content type: Research

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  6. A gamma-glutamyl transpeptidase (GGT) is produced by up to 31% of strains of Campylobacter jejuni isolates. C. jejuni GGT is close to Helicobacter pylori GGT suggesting a conserved activity but unlike the latter,...

    Authors: Pauline Floch, Vincent Pey, Michel Castroviejo, Jean William Dupuy, Marc Bonneu, Anaïs Hocès de la Guardia, Vincent Pitard, Francis Mégraud and Philippe Lehours

    Citation: Gut Pathogens 2014 6:20

    Content type: Research

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  7. Following peroral Toxoplasma (T.) gondii infection, susceptible mice develop acute ileitis due to a microbiota-dependent Th1 type immunopathology. Toll-like-receptor (TLR)-9 is known to recognize bacterial DNA an...

    Authors: Stefan Bereswill, Anja A Kühl, Marie Alutis, André Fischer, Luisa Möhle, Daniela Struck, Oliver Liesenfeld, Ulf B Göbel, Ildikò R Dunay and Markus M Heimesaat

    Citation: Gut Pathogens 2014 6:19

    Content type: Research

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  8. Poultry represent an important source of foodborne enteropathogens, in particular thermophilic Campylobacter species. Many of these organisms colonize the intestinal tract of broiler chickens as harmless commensa...

    Authors: Nadeem O Kaakoush, Nidhi Sodhi, Jeremy W Chenu, Julian M Cox, Stephen M Riordan and Hazel M Mitchell

    Citation: Gut Pathogens 2014 6:18

    Content type: Research

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  9. Campylobacter jejuni has emerged as a leading cause of bacterial enterocolitis. The serine protease HtrA has been shown to be a pivotal, novel C. jejuni virulence factor involved in cell invasion and transmigrati...

    Authors: Markus M Heimesaat, André Fischer, Marie Alutis, Ursula Grundmann, Manja Boehm, Nicole Tegtmeyer, Ulf B Göbel, Anja A Kühl, Stefan Bereswill and Steffen Backert

    Citation: Gut Pathogens 2014 6:16

    Content type: Research

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  10. Bacteria respond to elevated osmolality by the accumulation of a range of low molecular weight molecules, known as compatible solutes (owing to their compatibility with the cells' normal physiology at high int...

    Authors: Audrey Feeney, Christopher D Johnston, Rodney Govender, Jim O’Mahony, Aidan Coffey and Roy D Sleator

    Citation: Gut Pathogens 2014 6:15

    Content type: Research

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  11. This paper presents a functional nanoparticle-enhanced enzyme-linked immunosorbent assay (FNP-ELISA) for detection of enterohemorrhagic Escherichia coli (EHEC) O157:H7. Immunomagnetic nanoparticles (IMMPs) conjug...

    Authors: Zhiqiang Shen, Nannan Hou, Min Jin, Zhigang Qiu, Jingfeng Wang, Bin Zhang, Xinwei Wang, Jie Wang, Dongsheng Zhou and Junwen Li

    Citation: Gut Pathogens 2014 6:14

    Content type: Research

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  12. Multidrug resistance and, in particular, carbapenem resistance is spreading worldwide at an alarming rate, comprehending a variety of bacterial species and causing both nosocomial and community acquired outbur...

    Authors: Andrea Bartolini, Ilaria Frasson, Antonietta Cavallaro, Sara N Richter and Giorgio Palù

    Citation: Gut Pathogens 2014 6:13

    Content type: Research

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  13. Thermotolerant Campylobacter jejuni, coli and lari are recognized as leading food-borne pathogens causing an acute bacterial enteritis worldwide. Due to narrow spectrum of their biochemical activity, it is very c...

    Authors: Lucie Vondrakova, Jarmila Pazlarova and Katerina Demnerova

    Citation: Gut Pathogens 2014 6:12

    Content type: Research

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  14. Authors: Yalda Khosravi, Vellaya Rehvathy, Wei Yee Wee, Susana Wang, Primo Baybayan, Siddarth Singh, Meredith Ashby, Junxian Ong, Arlaine Anne Amoyo, Shih Wee Seow, Siew Woh Choo, Tim Perkins, Eng Guan Chua, Alfred Tay, Barry James Marshall, Mun Fai Loke…

    Citation: Gut Pathogens 2014 6:11

    Content type: Erratum

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    The original article was published in Gut Pathogens 2013 5:25

  15. Helicobacter pylori infection that is usually acquired in childhood and lasts for lifetime is mostly asymptomatic but associated with severe gastrointestinal disease including cancer. During chronic infection, th...

    Authors: Angelika Michel, Michael Pawlita, Heiner Boeing, Lutz Gissmann and Tim Waterboer

    Citation: Gut Pathogens 2014 6:10

    Content type: Research

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  16. The genus Salmonella is Gram-negative which belongs to the family Enterobacteriaceae. In this study, we have sequenced the whole genome of the strain DMA-1, which was isolated from mouse stool sample and identifi...

    Authors: Sathyaseelan Sathyabama, Gurwinder Kaur, Amit Arora, Sheenam Verma, Nida Mubin, Shanmugam Mayilraj and Javed N Agrewala

    Citation: Gut Pathogens 2014 6:8

    Content type: Genome Announcement

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  17. Public Health England (PHE) holds a collection of Shigella flexneri Type strains isolated between 1949 and 1972 representing 15 established serotypes and one provisional type, E1037. In this study, the genomes of...

    Authors: Philip M Ashton, Kate S Baker, Amy Gentle, David J Wooldridge, Nicholas R Thomson, Timothy J Dallman and Claire Jenkins

    Citation: Gut Pathogens 2014 6:7

    Content type: Short report

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  18. Helicobacter pylori is well known for its relationship with the occurrence of several severe gastric diseases. The mechanisms of pathogenesis triggered by H. pylori are less well known. In this study, we report t...

    Authors: Yuanhai You, Lin Liu, Maojun Zhang, Yuanfang Zhu, Lihua He, Dongfang Li and Jianzhong Zhang

    Citation: Gut Pathogens 2014 6:5

    Content type: Genome Announcement

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  19. Clostridium difficile is the leading cause of infectious diarrhea in humans and responsible for large outbreaks of enteritis in neonatal pigs in both North America and Europe. Disease caused by C. difficile typic...

    Authors: Aaron E Darling, Paul Worden, Toni A Chapman, Piklu Roy Chowdhury, Ian G Charles and Steven P Djordjevic

    Citation: Gut Pathogens 2014 6:4

    Content type: Genome Announcement

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  20. Vibrio cholerae is a human intestinal pathogen and V. cholerae of the O139 serogroups are responsible for the current epidemic cholera in China. In this work, we reported the whole genome sequencing of a V. chole...

    Authors: Yong Yi, Na Lu, Fei Liu, Jing Li, Ruifen Zhang, Liping Jia, Hua Jing, Hu Xia, Yi Yang, Baoli Zhu, Yongfei Hu and Yan Cui

    Citation: Gut Pathogens 2014 6:3

    Content type: Genome Announcement

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  21. Probiotics are commonly used as feed additive to substitute antibiotic as growth promoter in animal farming. Probiotic consists of lactic acid bacteria (LAB), which enhance the growth and health of the animal....

    Authors: Nurhazirah Shazali, Hooi Ling Foo, Teck Chwen Loh, Di Wei Choe and Raha Abdul Rahim

    Citation: Gut Pathogens 2014 6:1

    Content type: Research

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  22. Salmonella is often implicated in foodborne outbreaks, and is a major public health concern in the United States and throughout the world. Salmonella enterica serovar Enteritidis (SE) infection in humans is often...

    Authors: Daniel C Shippy, Nicholas M Eakley, Dareen M Mikheil and Amin A Fadl

    Citation: Gut Pathogens 2013 5:43

    Content type: Research

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  23. Widely considered probiotic organisms, Bifidobacteria are common inhabitants of the alimentary tract of animals including insects. Bifidobacteria identified from the honey bee are found in larval guts and through...

    Authors: Kirk E Anderson, Andreas Johansson, Tim H Sheehan, Brendon M Mott, Vanessa Corby-Harris, Laurel Johnstone, Ryan Sprissler and William Fitz

    Citation: Gut Pathogens 2013 5:42

    Content type: Genome Announcement

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  24. Campylobacter enteritis has emerged as one of the most common forms of human diarrheal illness. In this study we have investigated the virulence potential of five new C. jejuni chicken isolates (RO14, RO19, RO24,...

    Authors: Lavinia Stef, Ada Cean, Aida Vasile, Calin Julean, Dan Drinceanu and Nicolae Corcionivoschi

    Citation: Gut Pathogens 2013 5:41

    Content type: Research

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  25. Acute appendicitis is a surgical emergency in which the appendix is surgically removed to prevent peritonitis due to perforation of the appendix. Depending on age and gender, up to 17% of removed appendices do...

    Authors: Laurens J Westerman, Marguerite EI Schipper, Herbert V Stel, Marc JM Bonten and Johannes G Kusters

    Citation: Gut Pathogens 2013 5:40

    Content type: Short report

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  26. From a clinical perspective, it is important to know which serogroups, virulence genes and antibiotic resistance patterns are present in Shiga toxin-producing Escherichia coli strains in pediatric patients suffer...

    Authors: Hassan Momtaz, Farhad Safarpoor Dehkordi, Mohammad Javad Hosseini, Meysam Sarshar and Maliheh Heidari

    Citation: Gut Pathogens 2013 5:39

    Content type: Research

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  27. Vibrio parahaemolyticus, an important human pathogen, is associated with gastroenteritis and transmitted through partially cooked seafood. It has become a major concern in the production and trade of marine food ...

    Authors: Suma Tiruvayipati, Subha Bhassu, Narender Kumar, Ramani Baddam, Sabiha Shaik, Anil Kumar Gurindapalli, Kwai Lin Thong and Niyaz Ahmed

    Citation: Gut Pathogens 2013 5:37

    Content type: Research

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  28. This study was conducted to determine the role of enteroaggregative Escherichia coli (EAEC) in inflammatory diarrhea among hospitalized patients in Kolkata. The inflammatory pathogenesis of EAEC was established i...

    Authors: Dhira Rani Saha, Sucharita Guin, Rajendran Krishnan, Dhrubajyoti Nag, Hemanta Koley, Sumio Shinoda and Thandavarayan Ramamurthy

    Citation: Gut Pathogens 2013 5:36

    Content type: Research

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  29. Plasmid-encoded extended-spectrum beta-lactamase (ESBL)-enzymes are frequently produced by Escherichia coli. Several ESBL-plasmids contain genes for toxin-antitoxin (TA) systems, which assure the maintenance of p...

    Authors: Katharina Schaufler, Lothar H Wieler, Torsten Semmler, Christa Ewers and Sebastian Guenther

    Citation: Gut Pathogens 2013 5:34

    Content type: Short report

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  30. The cagA gene is one of the important virulence factors of Helicobacter pylori. The diversity of cagA 5′ conserved region is thought to reflect the phylogenetic relationships between different H. pylori isolates ...

    Authors: Barik A Salih, Bora Kazim Bolek, Mehmet Taha Yildiz and Soykan Arikan

    Citation: Gut Pathogens 2013 5:33

    Content type: Short report

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  31. Propionic acid (PA) found in some foods and formed as a metabolic product of gut bacteria has been reported to mimic/mediate the effects of autism. The present study was undertaken to compare the effect of ora...

    Authors: Afaf El-Ansary, Ghada Shaker, Nikhat J Siddiqi and Laila Y Al-Ayadhi

    Citation: Gut Pathogens 2013 5:32

    Content type: Research

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  32. Different strategies of colonization or infection by E. coli result in formation of certain adhesion patterns which help also in classifying intestinal E. coli into pathotypes. Little is known about adhesion patt...

    Authors: Ulrike Frömmel, Alexander Böhm, Jörg Nitschke, Jörg Weinreich, Julia Groß, Stefan Rödiger, Thomas Wex, Hermann Ansorge, Olaf Zinke, Christian Schröder, Dirk Roggenbuck and Peter Schierack

    Citation: Gut Pathogens 2013 5:31

    Content type: Research

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  33. The yeast Saccharomyces boulardii is used worldwide as a probiotic to alleviate the effects of several gastrointestinal diseases and control antibiotics-associated diarrhea. While many studies report the probioti...

    Authors: Indu Khatri, Akil Akhtar, Kamaldeep Kaur, Rajul Tomar, Gandham Satyanarayana Prasad, Thirumalai Nallan Chakravarthy Ramya and Srikrishna Subramanian

    Citation: Gut Pathogens 2013 5:30

    Content type: Research

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  34. Serratia marcescens is an opportunistic bacterial pathogen with broad range of host ranging from vertebrates, invertebrates and plants. S. marcescens strain W2.3 was isolated from a diseased tilapia fish and it w...

    Authors: Xin Yue Chan, Chien Yi Chang, Kar Wai Hong, Kok Keng Tee, Wai Fong Yin and Kok Gan Chan

    Citation: Gut Pathogens 2013 5:29

    Content type: Genome Announcement

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  35. Three pathogenicity islands, viz. SPI-1 (Salmonella pathogenicity island 1), SPI-2 (Salmonella pathogenicity island 2) and T6SS (Type VI Secretion System), present in the genome of Salmonella typhimurium have bee...

    Authors: Chandrani Das, Anirban Dutta, Hannah Rajasingh and Sharmila S Mande

    Citation: Gut Pathogens 2013 5:28

    Content type: Research

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  36. Recent studies of Giardia lamblia outbreaks have indicated that 40–80% of infected patients experience long-lasting functional gastrointestinal disorders after parasitic clearance. Our aim was to assess changes i...

    Authors: Tzu-Ling Chen, Shin Chen, Hsiu-Wei Wu, Tsung-Chun Lee, Yen-Zhen Lu, Li-Ling Wu, Yen-Hsuan Ni, Chin-Hung Sun, Wei-Hsuan Yu, Andre G Buret and Linda Chia-Hui Yu

    Citation: Gut Pathogens 2013 5:26

    Content type: Research

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  37. Helicobacter pylori is a Gram-negative bacterium that persistently infects the human stomach inducing chronic inflammation. The exact mechanisms of pathogenesis are still not completely understood. Although not a...

    Authors: Yalda Khosravi, Vellaya Rehvathy, Wei Yee Wee, Susana Wang, Primo Baybayan, Siddarth Singh, Meredith Ashby, Junxian Ong, Arlaine Anne Amoyo, Shih Wee Seow, Siew Woh Choo, Tim Perkins, Eng Guan Chua, Alfred Tay, Barry James Marshall, Mun Fai Loke…

    Citation: Gut Pathogens 2013 5:25

    Content type: Genome Announcement

    Published on:

    The Erratum to this article has been published in Gut Pathogens 2014 6:11

  38. Brachyspira pilosicoli is an anaerobic spirochaete that can colonizes the large intestine of many host species. Infection is particularly problematic in pigs and adult poultry, causing colitis and diarrhea, but i...

    Authors: Eugene Neo, Tom La, Nyree Dale Phillips, Mohammad Yousef Alikani and David J Hampson

    Citation: Gut Pathogens 2013 5:24

    Content type: Research

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    The Correction to this article has been published in Gut Pathogens 2019 11:50

  39. Human rotavirus (HRV) is the most important cause of severe diarrhea in infants and young children. Probiotic Lactobacillus rhamnosus GG (LGG) reduces rotavirus infection and diarrhea. However, the molecular mech...

    Authors: Shaoping Wu, Lijuan Yuan, Yongguo Zhang, Fangning Liu, Guohua Li, Ke Wen, Jacob Kocher, Xingdong Yang and Jun Sun

    Citation: Gut Pathogens 2013 5:22

    Content type: Research

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  40. Shigella species are a common cause of acute diarrheal disease in China. In this study, we characterized the changing trends and serotype distribution of Shigella species in Beijing from 1994 to 2010. A total of ...

    Authors: Yuanli Mao, Enbo Cui, Chunmei Bao, Zhenhong Liu, Suming Chen, Juling Zhang, Huan Wang, Chenglong Zhang, Jing Zou, John D Klena, Baoli Zhu, Fen Qu and Zhiyun Wang

    Citation: Gut Pathogens 2013 5:21

    Content type: Research

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  41. Vibrio fluvialis is an emerging diarrheal pathogen for which no genome is currently available. In this work, draft genomes of two closely related clinical strains PG41 and I21563 have been explored.

    Authors: Indu Khatri, Sakshi Mahajan, Chetna Dureja, Srikrishna Subramanian and Saumya Raychaudhuri

    Citation: Gut Pathogens 2013 5:20

    Content type: Genome Announcement

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  42. In vivo bioluminescence imaging (BLI) is a powerful method for the analysis of host-pathogen interactions in small animal models. The commercially available bioluminescent Listeria monocytogenes strain Xen32 is c...

    Authors: Silke Bergmann, Manfred Rohde, Klaus Schughart and Andreas Lengeling

    Citation: Gut Pathogens 2013 5:19

    Content type: Short report

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