Table 3 Metabolites concentration (mM) and ratios (%) measured by HPLC in model 2 during antibiotic treatment [A, B and E] and recovery [F] periods
| Â | Acetate | Propionate | Butyrate | Formate | Total metabolites | SCFA Ratios (%) | ||
|---|---|---|---|---|---|---|---|---|
Acetate | Propionate | Butyrate | ||||||
Period A (CRO I) | ||||||||
 CR | 75.7 ± 4.8 | 33.4 ± 2.5 | 38.4 ± 2.2 | ND | 147.5 ± 5.8 | 51.3 | 22.6 | 26.0 |
 TR1 | 75.0 ± 3.0 | 36.7 ± 4.0 | 37.4 ± 0.9 | ND | 148.4 ± 6.4 | 20.5 | 24.7 | 24.7 |
 TR3 | 76.5 ± 4.1 | 33.5 ± 2.0 | 35.8 ± 1.3 | ND | 145.8 ± 4.7 | 52.5 | 23.0 | 24.6 |
Period B (CRO II) | ||||||||
 CR | 91.2 ± 0.9 | 43.6 ± 2.2 | 18.4 ± 4.6 | ND | 153.2 ± 5.2 | 59.5 | 28.5 | 12.0 |
 TR1 | 93.5 ± 7.4 | 47.2 ± 4.3 | 19.5 ± 2.6 | ND | 160.2 ± 8.9 | 58.4 | 29.5 | 12.2 |
 TR3 | 97.0 ± 5.1* | 45.6 ± 4.3 | 19.6 ± 2.1 | ND | 162.2 ± 7.0 | 97 | 45.6 | 19.6 |
Period E (MTZ) | ||||||||
 CR | 99.2 ± 2.4 | 37.0 ± 1.2 | 13.3 ± 0.5 | ND | 149.5 ± 2.7 | 66.4 | 24.7 | 8.9 |
 TR1 | 44.1 ± 0.7* | 35.9 ± 1.8 | ND | 10.6 ± 1.0 | 90.6 ± 2.2* | 55.1 | 44.9 | 0 |
 TR4 | 45.6 ± 2.5* | 37.0 ± 1.3 | ND | 11.3 ± 1.6 | 93.9 ± 3.2* | 55.2 | 44.8 | 0 |
Period F (REC) | ||||||||
 CR | 92.6 ± 10.9 | 39.9 ± 6.2 | 13.4 ± 0.2 | ND | 145.9 ± 12.5 | 63.5 | 27.3 | 9.2 |
 TR1 | 83.7 ± 0.4 | 43.8 ± 2.4 | 13.4 ± 0.7 | ND | 140.9 ± 2.5 | 59.4 | 31.1 | 9.5 |
 TR4 | 88.4 ± 8.6 | 44.8 ± 9.8 | 13.5 ± 1.6 | ND | 146.7 ± 13.1 | 60.3 | 30.5 | 9.2 |