From: Transcriptome-wide association study identified candidate genes associated with gut microbiota
Gene | Tissue | Microbial trait | Z | P |
---|---|---|---|---|
NDUFV3 | Sigmoid colon | P_Lentisphaerae_HB | 3.61 | 1.35 × 10–3 |
Sigmoid colon | Div_NumberGenera_RNT | 3.52 | 1.58 × 10–3 | |
Sigmoid colon | G_O_Bacteroidales_HB | 3.45 | 1.96 × 10–3 | |
Sigmoid colon | G_Prevotella_HB | 3.25 | 1.99 × 10–3 | |
Sigmoid colon | G_O_Clostridiales_RNT | 3.33 | 2.01 × 10–3 | |
Sigmoid colon | Div_Chao1_RNT | 3.18 | 2.48 × 10–3 | |
Transverse colon | P_Lentisphaerae_HB | 3.41 | 2.51 × 10–3 | |
Transverse colon | G_O_Clostridiales_RNT | 3.20 | 3.19 × 10–3 | |
Sigmoid colon | G_F_Ruminococcaceae_RNT | 3.35 | 3.65 × 10–3 | |
Sigmoid colon | G_Victivallis_HB | 3.08 | 4.37 × 10–3 | |
Transverse colon | G_O_Bacteroidales_HB | 2.98 | 4.64 × 10–3 | |
Sigmoid colon | G_Bacteroides_RNT | − 3.22 | 5.11 × 10–3 | |
Transverse colon | G_Bacteroides_RNT | − 3.30 | 6.08 × 10–3 | |
Sigmoid colon | G_Sporobacter_RNT | 3.26 | 1.01 × 10–2 | |
Sigmoid colon | G_P_Bacteroidetes_HB | 2.85 | 1.14 × 10–2 | |
SH3PXD2B | Sigmoid colon | Div_Shannon_RNT | − 4.04 | 1.26 × 10–3 |
Sigmoid colon | Div_Chao1_RNT | − 3.54 | 1.44 × 10–3 | |
Sigmoid colon | G_F_Ruminococcaceae_RNT | − 3.49 | 1.60 × 10–3 | |
Sigmoid colon | F_Desulfovibrionaceae_RNT | − 3.54 | 1.87 × 10–3 | |
Sigmoid colon | F_Porphyromonadaceae_RNT | − 4.02 | 2.04 × 10–3 | |
Sigmoid colon | Div_NumberGenera_RNT | − 3.46 | 2.58 × 10–3 | |
Sigmoid colon | G_Desulfovibrio_HB | − 3.42 | 2.64 × 10–3 | |
Sigmoid colon | C_Deltaproteobacteria_HB | − 3.16 | 3.33 × 10–3 | |
Sigmoid colon | G_O_Clostridiales_RNT | − 3.55 | 4.15 × 10–3 | |
Sigmoid colon | G_Barnesiella_HB | − 3.50 | 4.77 × 10–3 | |
Sigmoid colon | P_Lentisphaerae_HB | − 3.47 | 5.03 × 10–3 | |
Sigmoid colon | G_Oscillibacter_RNT | − 3.72 | 6.04 × 10–3 | |
RP3-388E23.2 | Transverse colon | G_Butyrivibrio_HB | 3.93 | 3.46 × 10–5 |
Transverse colon | Div_Shannon_RNT | 3.43 | 4.13 × 10–4 | |
Transverse colon | G_O_Clostridiales_RNT | 2.70 | 1.33 × 10–3 | |
Transverse colon | G_Clostridium_sensu_RNT | 2.71 | 2.73 × 10–3 | |
Transverse colon | G_F_Ruminococcaceae_RNT | 2.72 | 2.94 × 10–3 | |
Sigmoid colon | G_F_Ruminococcaceae_RNT | 2.61 | 5.84 × 10–3 | |
Sigmoid colon | G_F_Porphyromonadaceae_RNT | 2.56 | 7.77 × 10–3 | |
Sigmoid colon | G_Dorea_RNT | 2.06 | 1.04 × 10–2 | |
Transverse colon | G_P_Proteobacteria_HB | 2.43 | 1.21 × 10–2 | |
Sigmoid colon | G_Intestinibacter_HB | 2.08 | 1.98 × 10–2 | |
Transverse colon | G_Oscillibacter_RNT | 2.22 | 2.44 × 10–2 | |
CYP3A7 | Transverse colon | G_Bacteroides_RNT | − 2.46 | 6.27 × 10–6 |
Transverse colon | G_P_Proteobacteria_HB | 2.28 | 7.96 × 10–6 | |
Transverse colon | G_Methanobrevibacter_HB | 2.31 | 3.04 × 10–5 | |
Transverse colon | Div_Chao1_RNT | 2.76 | 3.29 × 10–5 | |
Transverse colon | Div_NumberGenera_RNT | 2.48 | 1.59 × 10–4 | |
Transverse colon | O_Burkholderiales_RNT | 2.60 | 2.94 × 10–4 | |
Transverse colon | G_Victivallis_RNT | 2.26 | 4.90 × 10–4 | |
Transverse colon | Div_Shannon_RNT | 2.45 | 6.20 × 10–4 | |
Transverse colon | G_Gemmiger_HB | 2.68 | 6.51 × 10–4 | |
Transverse colon | G_Methanobrevibacter_HB | 2.19 | 9.41 × 10–4 | |
WDR5B | Sigmoid colon | F_Veillonellaceae_HB | − 3.20 | 4.99 × 10–4 |
Transverse colon | G_F_Porphyromonadaceae_RNT | 3.31 | 2.00 × 10–3 | |
Sigmoid colon | G_F_Porphyromonadaceae_RNT | 3.35 | 2.05 × 10–3 | |
Sigmoid colon | O_Rhodospirillales_HB | 3.20 | 3.45 × 10–3 | |
Sigmoid colon | G_O_Clostridiales_RNT | 2.37 | 3.57 × 10–3 | |
Sigmoid colon | C_Alphaproteobacteria_HB | 3.37 | 3.91 × 10–3 | |
Sigmoid colon | G_P_Proteobacteria_RNT | − 2.51 | 4.66 × 10–3 | |
Transverse colon | F_Acidaminococcaceae_RNT | − 2.49 | 4.75 × 10–3 | |
Sigmoid colon | F_Rhodospirillaceae_HB | 2.97 | 4.80 × 10–3 | |
Sigmoid colon | G_F_Rhodospirillaceae_HB | 2.76 | 6.18 × 10–3 | |
DFNB59 | Sigmoid colon | G_F_Porphyromonadaceae_HB | − 3.67 | 7.08 × 10–5 |
Sigmoid colon | G_Akkermansia_HB | − 2.64 | 6.56 × 10–4 | |
Sigmoid colon | F_Desulfovibrionaceae_RNT | − 3.30 | 8.33 × 10–4 | |
Sigmoid colon | G_Oscillibacter_RNT | − 3.87 | 8.78 × 10–4 | |
Sigmoid colon | G_Victivallis_HB | − 2.99 | 1.42 × 10–3 | |
Sigmoid colon | G_O_Clostridiales_RNT | − 3.13 | 1.97 × 10–3 | |
Sigmoid colon | G_F_Coriobacteriaceae_HB | − 2.99 | 2.54 × 10–3 | |
Sigmoid colon | G_Alistipes_RNT | − 2.85 | 2.91 × 10–3 | |
Sigmoid colon | G_Eisenbergiella_HB | − 2.12 | 3.39 × 10–3 |