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Table 4 Antimicrobial susceptibility of S. flexneri clinical isolates

From: Virulence genes expression profiling of different Shigella flexneri serotypes in response to sub-inhibitory concentrations of azithromycin and ciprofloxacin

Antimicrobial agents

S. flexneri clinical isolates

S

I

SDD

R

Penicillins

Ampicillin

1 (1%)

0 (0%)

–

96 (99%)

Cephems

Cefotaxime

49 (50.5%)

2 (2.1%)

–

46 (47.4%)

Cefepime

55 (56.7)

–

9 (9.3%)

33 (34%)

Folate pathway antagonists

Trimethoprim-sulfamethoxazole

5 (5.2%)

5 (5.2%)

–

87 (89.7%)

Macrolides

Azithromycin

87 (89.7%)

1 (1%)

–

9 (%9.3)

Quinolones and fluoroquinolones

Ciprofloxacin

87 (89.7%)

3 (3.1%)

–

7 (7.2%)

Nalidixic acid

46 (47.4%)

21 (21.6%)

–

30 (30.9%)

Tetracyclines

Minocycline

51 (52.6%)

18 (18.6%)

–

28 (28.9%)

  1. Antimicrobial susceptibility test evaluated for antibiotics using Kirby–Bauer disk
  2. Diffusion method (S, sensitive; SDD, susceptible, dose dependent; I, intermediate; R, resistant)