Figure 1
From: Probiotics and gastrointestinal disease: successes, problems and future prospects
Recent advances in the design of more effective probiotic cultures by (A) improving probiotic tolerance to stresses encountered during food manufacture and storage. (B) Improving in vivo resistance to host specific stresses, thus facilitating improved gut colonization and persistence and (C) designer probiotics which specifically target pathogens and/or toxins; thus improving prophylactic and therapeutic effect [52].