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Table 6 Comparison of prevalences of Helicobacter-positivity, by urea-breath-test (UBT) and serology, between probands with idiopathic parkinsonism and their spouses and controls.

From: Blood profile holds clues to role of infection in a premonitory state for idiopathic parkinsonism and of gastrointestinal infection in established disease

 

Helicobacter-positivity (%)

Test

Probands

Spouses

Controls

 

Phase-1†

Phase-2††

Phase-1

Phase-2††

Phase-1†

Phase-2

 

n = 120

n = 118

 

n = 86a

n = 196b

 

UBT

-

29.6

-

16.9

-

-

ELISA

47.6

34.5

-

18.4

39.5

-

Immunoblotc

36.7

50.0

-

34.2

30.8

-

  1. aincluding 8 with clinically-definite IP.
  2. bwithout clinically-definite IP.
  3. cequivocal score in a further 8.2% of Phase 2 subjects.
  4. † prevalence of seropositivity not significantly different. Both ELISA and immunoblot available in 196 of 205 controls.
  5. †† p = 0.1, 0.06 & 0.06 (age & gender adjusted) for comparison of prevalence of positive-status by UBT, ELISA & immunoblot, respectively.
  6. N.B. Absolute change in prevalence of Helicobacter not addressed since IP-cohorts not matched for locality/social class.
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Gut Pathogens

ISSN: 1757-4749